Document Detail


The Maastricht Study: an extensive phenotyping study on determinants of type 2 diabetes, its complications and its comorbidities.
MedLine Citation:
PMID:  24756374     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The Maastricht Study is an extensive phenotyping study that focuses on the etiology of type 2 diabetes (T2DM), its classic complications, and its emerging comorbidities. The study uses state-of-the-art imaging techniques and extensive biobanking to determine health status in a population-based cohort of 10,000 individuals that is enriched with T2DM individuals. Enrollment started in November 2010 and is anticipated to last 5-7 years. The Maastricht Study is expected to become one of the most extensive phenotyping studies in both the general population and T2DM participants world-wide. The Maastricht study will specifically focus on possible mechanisms that may explain why T2DM accelerates the development and progression of classic complications, such as cardiovascular disease, retinopathy, neuropathy and nephropathy and of emerging comorbidities, such as cognitive decline, depression, and gastrointestinal, musculoskeletal and respiratory diseases. In addition, it will also examine the association of these variables with quality of life and use of health care resources. This paper describes the rationale, overall study design, recruitment strategy and methods of basic measurements, and gives an overview of all measurements that are performed within The Maastricht Study.
Authors:
Miranda T Schram; Simone J S Sep; Carla J van der Kallen; Pieter C Dagnelie; Annemarie Koster; Nicolaas Schaper; Ronald M A Henry; Coen D A Stehouwer
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-4-23
Journal Detail:
Title:  European journal of epidemiology     Volume:  -     ISSN:  1573-7284     ISO Abbreviation:  Eur. J. Epidemiol.     Publication Date:  2014 Apr 
Date Detail:
Created Date:  2014-4-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8508062     Medline TA:  Eur J Epidemiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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