Document Detail


MT neurons combine visual motion with a smooth eye movement signal to code depth-sign from motion parallax.
MedLine Citation:
PMID:  19709633     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The capacity to perceive depth is critical for an observer to interact with his or her surroundings. During observer movement, information about depth can be extracted from the resulting patterns of image motion on the retina (motion parallax). Without extraretinal signals related to observer movement, however, depth-sign (near versus far) from motion parallax can be ambiguous. We previously demonstrated that MT neurons combine visual motion with extraretinal signals to code depth-sign from motion parallax in the absence of other depth cues. In that study, head translations were always accompanied by compensatory tracking eye movements, allowing at least two potential sources of extraretinal input. We now show that smooth eye movement signals provide the critical extraretinal input to MT neurons for computing depth-sign from motion parallax. Our findings demonstrate a powerful modulation of MT activity by eye movements, as predicted by human studies of depth perception from motion parallax.
Authors:
Jacob W Nadler; Mark Nawrot; Dora E Angelaki; Gregory C DeAngelis
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  Neuron     Volume:  63     ISSN:  1097-4199     ISO Abbreviation:  Neuron     Publication Date:  2009 Aug 
Date Detail:
Created Date:  2009-08-27     Completed Date:  2009-09-21     Revised Date:  2012-02-28    
Medline Journal Info:
Nlm Unique ID:  8809320     Medline TA:  Neuron     Country:  United States    
Other Details:
Languages:  eng     Pagination:  523-32     Citation Subset:  IM    
Affiliation:
Department of Anatomy & Neurobiology, Washington University School of Medicine, St. Louis, MO 63110, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Depth Perception / physiology*
Eye Movements / physiology*
Macaca mulatta
Male
Motion Perception / physiology*
Neurons / physiology*
Photic Stimulation / methods*
Retina / physiology
Temporal Lobe / cytology,  physiology
Visual Cortex / cytology,  physiology*
Grant Support
ID/Acronym/Agency:
5-T32-EY13360-07/EY/NEI NIH HHS; EY013644/EY/NEI NIH HHS; EY017866/EY/NEI NIH HHS; P20 RR020151-06A1/RR/NCRR NIH HHS; R01 EY013644-09/EY/NEI NIH HHS; R01 EY017866-03/EY/NEI NIH HHS
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