Document Detail


MRI versus CT in the diagnosis of Nelson's syndrome.
MedLine Citation:
PMID:  9000409     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The purpose of the study was to evaluate the utility of MRI and CT in the diagnosis of Nelson's syndrome, i. e. pituitary tumours in patients bilaterally adrenalectomized for Cushing's disease. Thirteen patients, followed up for 5-29 years after adrenalectomy, were studied. In 6 of them CT and MRI revealed no changes in the pituitary gland. In the remaining 7 patients only three CT scans were suggestive of a pituitary adenoma. MRI studies with administration of gadodiamide confirmed the CT diagnosis of Nelson's tumour in 3 patients and disclosed microadenomas in a further 4 patients. Neurosurgical treatment in 4 patients confirmed the MRI findings. Additionally CT and MRI examinations were performed in 5 patients suspected of a recurrent Nelson's tumour 3-11 years after neurosurgery. MRI visualized recurrent adenomas in 3 patients that were not well seen by CT scans. In our experience MRI was more effective than CT in the diagnosis of Nelson's syndrome.
Authors:
A Kasperlik-Zaluska; J Walecki; J Brzeziński; W Jeske; B Migdalska; W Bonicki; A Brzezińska; A Makowska
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European radiology     Volume:  7     ISSN:  0938-7994     ISO Abbreviation:  Eur Radiol     Publication Date:  1997  
Date Detail:
Created Date:  1997-03-14     Completed Date:  1997-03-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9114774     Medline TA:  Eur Radiol     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  106-9     Citation Subset:  IM    
Affiliation:
Department of Endocrinology, Centre of Postgraduate Medical Education, Ceglowska 80, 01-809 Warsaw, Poland.
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MeSH Terms
Descriptor/Qualifier:
Adrenalectomy / adverse effects
Adult
Aged
Cushing Syndrome / complications,  surgery
Female
Follow-Up Studies
Humans
Magnetic Resonance Imaging*
Male
Middle Aged
Nelson Syndrome / diagnosis*,  etiology
Pituitary Gland / pathology,  radiography
Tomography, X-Ray Computed*

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