Document Detail


MRI to study embryonic development.
MedLine Citation:
PMID:  21874499     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Non-invasive imaging of embryonic development has been an ultimate goal for embryologists for many years. Due to advances in MRI hardware and software, the extremely high spatial resolution necessary to study embryos can now be obtained. Fixed embryos can be scanned to visualize the complex 3D morphology of the developing embryo in great detail, sometimes referred to as MR histology. As the sample remains intact, it is a suitable tool for the study of rare specimens, or for screening of huge numbers of transgenic embryos. In vivo MRI can be used for time course studies of either normal development or the progression of congenital malformations.
Authors:
Bianca Hogers
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Methods in molecular biology (Clifton, N.J.)     Volume:  771     ISSN:  1940-6029     ISO Abbreviation:  Methods Mol. Biol.     Publication Date:  2011  
Date Detail:
Created Date:  2011-08-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9214969     Medline TA:  Methods Mol Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  579-93     Citation Subset:  IM    
Affiliation:
Department of Anatomy, Leiden University Medical Center, 2300 RC, Leiden, The Netherlands, b.hogers@lumc.nl.
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