| An MRI study of septi pellucidi in relation to hippocampus volume and fornix integrity in schizophrenia. | |
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MedLine Citation:
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PMID: 22177349 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Septum pellucidum (SP) and cavum SP (CSP) were delineated in two samples. The Longitudinal Study examined structural MR-images in first-episode schizophrenia (FESZ) and controls at two time-points. The Cross-Sectional Study examined structural and diffusion-tensor MR measures, including hippocampus and fornix, in chronic schizophrenia (SZ) at one time-point. CSP and SP measurements remained stable over time in FESZ and controls. Compared to controls, CSP were smaller in FESZ, but not in chronic SZ. SP were larger in chronic SZ, but not in FESZ. In chronic SZ only, SP-Length was correlated negatively with fornix-FA and hippocampal volume, and positively with chlorpromazine-equivalent dosage. |
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Authors:
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Charlie A Davidson; Noriomi Kuroki; Jorge L Alvarado; Margaret A Niznikiewicz; Robert W McCarley; James J Levitt |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-12-14 |
Journal Detail:
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Title: Schizophrenia research Volume: - ISSN: 1573-2509 ISO Abbreviation: - Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2011-12-19 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8804207 Medline TA: Schizophr Res Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 Elsevier B.V. All rights reserved. |
Affiliation:
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Psychiatry Neuroimaging Laboratory, Brigham and Women's Hospital, Harvard Medical School, 1249 Boylston St., Boston, MA 02215, United States. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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