| MRI for staging lymphoma: Whole-body or less? | |
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MedLine Citation:
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PMID: 21509873 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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PURPOSE: To assess whether whole-body MRI detects more clinically relevant lesions (i.e., leading to a change in Ann Arbor stage) than an MRI protocol that only includes the head/neck and trunk (i.e., from cranial vertex to groin, excluding the arms) in patients with lymphoma. MATERIALS AND METHODS: One hundred consecutive patients with newly diagnosed lymphoma prospectively underwent T1-weighted and T2-weighted short inversion time inversion recovery whole-body MRI. The number of lymphomatous sites at MRI with a field of view (FOV) limited to the head/neck and trunk, and the additional number of lymphomatous sites at whole-body MRI and their influence on Ann Arbor stage were determined. RESULTS: At MRI with a FOV limited to the head/neck and trunk, 507 sites were classified as lymphomatous. At whole-body MRI, 7 additional sites outside the head/neck and trunk in 7 patients (7.0%; 95% confidence interval: 3.4-13.8%) were classified as lymphomatous, but Ann Arbor stage never changed. CONCLUSION: Whole-body MRI did not detect any clinically relevant lesions outside the FOV of an MRI protocol that only includes the head/neck and trunk. Therefore, it may be sufficient to only include the head/neck and trunk when using MRI for staging lymphoma. J. Magn. Reson. Imaging 2011;33:1144-1150. © 2011 Wiley-Liss, Inc. |
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Authors:
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Thomas C Kwee; Erik M Akkerman; Rob Fijnheer; Marie José Kersten; József Zsíros; Inge Ludwig; Marc B Bierings; Malou A Vermoolen; Maarten S van Leeuwen; Jaap Stoker; Rutger A J Nievelstein |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of magnetic resonance imaging : JMRI Volume: 33 ISSN: 1522-2586 ISO Abbreviation: J Magn Reson Imaging Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-04-21 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9105850 Medline TA: J Magn Reson Imaging Country: United States |
Other Details:
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Languages: eng Pagination: 1144-50 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 Wiley-Liss, Inc. |
Affiliation:
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Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands. thomaskwee@gmail.com. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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