Document Detail


MRI of recurrent isolated cerebral Whipple's disease.
MedLine Citation:
PMID:  19847772     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Whipple's disease is a rare systemic bacterial infection, characterized predominantly by gastrointestinal symptoms. Neurological symptoms are frequent in the course of the disease; however, a purely neurological presentation is uncommon. Diagnosis is confirmed with biopsy and polymerase chain reaction studies. Magnetic resonance imaging (MRI) findings vary, most commonly showing increased signal intensity on T2-weighted images. Contrast-enhanced images and diffusion- weighted imaging are useful to demonstrate meningeal enhancement and any accompanying infarcts. Brain biopsy is often performed, and MRI is crucial to guide the biopsy. Cerebral Whipple's disease is a long-lasting infection requiring long-term follow-up of these patients. MRI should be performed to detect any potential recurrence. We present a case of recurrent isolated cerebral Whipple's disease in a 68-year-old man with atypical presentation and MRI findings.
Authors:
Fuldem Yildirim D?nmez; Esra Ulu; Ceyla Ba?aran; M?ge Unl?kaplan; Arzu Uyu?ur; Mahir Yildirim; Esra Ozg?l
Publication Detail:
Type:  Journal Article     Date:  2009-10-21
Journal Detail:
Title:  Diagnostic and interventional radiology (Ankara, Turkey)     Volume:  16     ISSN:  1305-3612     ISO Abbreviation:  Diagn Interv Radiol     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-06-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101241152     Medline TA:  Diagn Interv Radiol     Country:  Turkey    
Other Details:
Languages:  eng     Pagination:  112-5     Citation Subset:  IM    
Affiliation:
Department of Radiology, Ba?kent University School of Medicine, Ankara, Turkey. fuldemyildirim@yahoo.com
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