Document Detail


MRI-radiofrequency tissue tagging in patients with aortic insufficiency before and after operation.
MedLine Citation:
PMID:  9564907     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Magnetic resonance imaging tissue tagging is a relatively recent methodology that describes ventricular systolic function in terms of intramyocardial ventricular deformation. Because the analysis involves the use of many intramyocardial points to describe systolic deformation, it is theoretically more sensitive at describing subtle differences in regional myocardial fiber shortening when compared with conventional measures of ventricular function such as wall thickening. The objectives of this study were (1) to define sensitive indices of ventricular systolic deformation to assist the clinician in the surgical evaluation of patients with aortic insufficiency, and (2) to quantify differences in regional systolic deformation before and after surgery for aortic insufficiency. METHODS: Magnetic resonance imaging with tissue tagging was performed on 10 normal volunteers and 8 patients with chronic severe aortic insufficiency. Follow-up postoperative studies (5.4+/-1.1 months) were obtained in 6 patients who underwent Ross procedure (1 patient), David procedure (1), and St. Jude aortic valve replacement (4). RESULTS: There was no significant difference in fractional area change, overall circumferential shortening, or overall radial thickening among the normal group, the preoperative aortic insufficiency group, or the postoperative aortic insufficiency group. However, on a regional basis, there was a decrease in posterior wall circumferential strains in the postoperative aortic insufficiency group (29%+/-13% preoperative aortic insufficiency (n=6) versus 24%+/-12% postoperative aortic insufficiency (n=6), p=0.02). CONCLUSIONS: On regional analysis, there was a small but significant decrease in posterior wall circumferential shortening after operation. Magnetic resonance imaging tissue tagging is a sensitive and clinically applicable method of quantifying regional ventricular wall function before and after intervention for aortic insufficiency.
Authors:
F F Ungacta; V G Dávila-Román; M J Moulton; B P Cupps; P Moustakidis; D S Fishman; R Actis; B A Szabo; D Li; N T Kouchoukos; M K Pasque
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  65     ISSN:  0003-4975     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  1998 Apr 
Date Detail:
Created Date:  1998-05-14     Completed Date:  1998-05-14     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  943-50     Citation Subset:  AIM; IM    
Affiliation:
Department of Surgery, Washington University, St. Louis, Missouri, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aortic Valve Insufficiency / diagnosis,  pathology,  physiopathology*,  surgery
Diastole
Evaluation Studies as Topic
Female
Follow-Up Studies
Heart Valve Prosthesis
Heart Valve Prosthesis Implantation
Heart Ventricles / pathology
Humans
Image Processing, Computer-Assisted / methods*
Magnetic Resonance Imaging / methods*
Male
Middle Aged
Muscle Fibers, Skeletal / physiology,  ultrastructure
Myocardial Contraction / physiology
Myocardium / pathology
Sensitivity and Specificity
Stress, Mechanical
Systole
Ventricular Function, Left / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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