Document Detail


MRI planimetry for diagnosis and follow-up of valve area in mitral stenosis treated with valvuloplasty.
MedLine Citation:
PMID:  16862504     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: We sought to determine whether noninvasive planimetry by magnetic resonance imaging (MRI) is suitably sensitive and reliable for visualizing the mitral valve area (MVA) and for detecting increases in the MVA after percutaneous balloon mitral valvuloplasty (PBMV). MATERIALS AND METHODS: In 8 patients with mitral valve stenosis, planimetry of the MVA was performed before and after PBMV with a 1.5 T MR scanner using a breath-hold balanced gradient echo sequence (True FISP). The data was compared to the echocardiographically determined MVA (ECHO-MVA) as well as to the invasively calculated MVA by the Gorlin formula at catheterization (CATH-MVA). RESULTS: PBMV was associated with an increase of 0.79 +/- 0.30 cm (2) in the MVA (Delta MRI-MVA). The correlation between Delta MRI-MVA and Delta CATH-MVA was 0.92 (p < 0.03) and that between Delta MRI-MVA and Delta ECHO-MVA was 0.90 (p < 0.04). The overall correlation between MRI-MVA and CATH-MVA was 0.95 (p < 0.0001) and that between MRI-MVA and ECHO-MVA was 0.98 (p < 0.0001). MRI-MVA slightly overestimated CATH-MVA by 8.0 % (1.64 +/- 0.45 vs. 1.51 +/- 0.49 cm (2), p < 0.01) and ECHO-MVA by 1.8 % (1.64 +/- 0.45 vs. 1.61 +/- 0.43 cm (2), n. s.). CONCLUSION: Magnetic resonance planimetry of the mitral valve orifice is a sensitive and reliable method for the noninvasive quantification of mitral stenosis and visualization of small relative changes in the MVA. This new method is therefore capable of diagnosing as well as following the course of mitral stenosis. It must be taken into consideration that planimetry by MRI slightly overestimates the MVA as compared to cardiac catheterization.
Authors:
B Djavidani; K Debl; S Buchner; C Lipke; W Nitz; S Feuerbach; G Riegger; A Luchner
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin     Volume:  178     ISSN:  1438-9029     ISO Abbreviation:  Rofo     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2006-07-24     Completed Date:  2006-09-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7507497     Medline TA:  Rofo     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  781-6     Citation Subset:  IM    
Affiliation:
Institut für Röntgendiagnostik, Universitätsklinikum Regensburg, Regensburg. behrus.djavidani@klinik.uni-regensburg.de
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MeSH Terms
Descriptor/Qualifier:
Anatomy, Cross-Sectional / methods*
Balloon Dilatation / methods*
Female
Follow-Up Studies
Humans
Image Interpretation, Computer-Assisted / methods*
Magnetic Resonance Imaging / methods*
Male
Middle Aged
Mitral Valve / pathology*
Mitral Valve Stenosis / diagnosis*,  therapy*
Prognosis
Reproducibility of Results
Sensitivity and Specificity
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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