| MRI nerve root enhancement in Krabbe disease. | |
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MedLine Citation:
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PMID: 9744639 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Krabbe disease is characterized by abnormal breakdown and turnover of myelin, leading to extensive demyelination in both the peripheral and central nervous systems. A 7-month-old infant with early-onset Krabbe disease had deceptively normal head images, but spinal MRI demonstrated abnormal gadolinium enhancement of the lumbosacral sacral nerve roots and cauda equina such as that seen in Guillain-Barré syndrome. Abnormal enhancement in spinal MRI has not been previously described in patients with leukodystrophies. |
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Authors:
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E Vasconcellos; M Smith |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Pediatric neurology Volume: 19 ISSN: 0887-8994 ISO Abbreviation: Pediatr. Neurol. Publication Date: 1998 Aug |
Date Detail:
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Created Date: 1998-12-04 Completed Date: 1998-12-04 Revised Date: 2006-05-23 |
Medline Journal Info:
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Nlm Unique ID: 8508183 Medline TA: Pediatr Neurol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 151-2 Citation Subset: IM |
Affiliation:
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Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee 37212, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cauda Equina
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pathology Humans Infant Leukodystrophy, Globoid Cell / diagnosis* Lumbosacral Region Magnetic Resonance Imaging* Male Spinal Nerve Roots / pathology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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