| MRI-negative epilepsy: Protocols to optimize lesion detection. | |
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MedLine Citation:
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PMID: 21732937 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Identification of the structural lesions that underlie pediatric epilepsy can be challenging. Careful evaluation of the gray-white matter interface is crucial, and necessitates multiplanar thin images of high resolution that can differentiate focal lesions from partial volume averaging artifacts created by the innate gyral configuration. Careful evaluation of the hippocampus and of the myelination patterns can further increase the diagnostic yield of the study. Magnetization transfer imaging can call attention to a lesion that is either very subtle or not evident on conventional sequences. Detection of cortical anomalies is best performed early in infancy, preferably before 6 months of age. If the initial magnetic resonance imaging (MRI) scan is performed between 9 and 18 months of age and is negative, a repeat scan after 2 years of age may be necessary. |
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Authors:
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Louis-Gilbert Vézina |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Epilepsia Volume: 52 Suppl 4 ISSN: 1528-1167 ISO Abbreviation: Epilepsia Publication Date: 2011 Jul |
Date Detail:
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Created Date: 2011-07-07 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 2983306R Medline TA: Epilepsia Country: United States |
Other Details:
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Languages: eng Pagination: 25-7 Citation Subset: IM |
Copyright Information:
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Wiley Periodicals, Inc. © 2011 International League Against Epilepsy. |
Affiliation:
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Department of Diagnostic Imaging and Radiology, Children's National Medical Center, Washington, District of Columbia, U.S.A. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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