Document Detail

MRI myocardial tagging.
MedLine Citation:
PMID:  10548769     Owner:  NLM     Status:  MEDLINE    
MRI myocardial tagging is now a well-developed method for evaluation of regional myocardial contraction. A series of progressively more refined imaging strategies, combined with advances in analytic strategies have provided a strong armamentarium of methods. Important insights into normal human physiology of left ventricular systolic and diastolic function have been developed using one-dimensional, two-dimensional and three-dimensional analyses of myocardial deformation. In disease states, improved understanding and detection of early alterations in myocardial function in hypertensive heart disease has been possible. In addition, improved understanding of effects of ischemia and infarction on regional function has been possible. Further, after acute myocardial infarction, clearer definition of the natural history of contractile dysfunction in the infarct region and the zone adjacent to the infarct have been possible. Similarly, effects on regional function of a number of important pharmacologic agents used for treatment, such as angiotensin converting enzyme inhibitors, beta blockers and angiotensin receptor blockers have been characterized. In the cardiomyopathies, myocardial tagging has permitted more reliable assessment of heterogeneity of segmental function, especially in hypertrophic cardiomyopathy. Finally, initial applications of myocardial tagging to assessment of right ventricular regional function in hypertrophied hearts with and without major congenital abnormalities have generated advances in understanding of effects of hypertrophy on right ventricular function.J. Magn. Reson. Imaging 1999;10:609-616.
N Reichek
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of magnetic resonance imaging : JMRI     Volume:  10     ISSN:  1053-1807     ISO Abbreviation:  J Magn Reson Imaging     Publication Date:  1999 Nov 
Date Detail:
Created Date:  2000-01-11     Completed Date:  2000-01-11     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9105850     Medline TA:  J Magn Reson Imaging     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  609-16     Citation Subset:  IM    
Copyright Information:
Copyright 1999 Wiley-Liss, Inc.
Division of Cardiology, Allegheny General Hospital, and Department of Medicine, MCP-Hahnemann School of Medicine, Pittsburgh, Pennsylvania 15212, USA.
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MeSH Terms
Coronary Disease / diagnosis
Heart / anatomy & histology
Heart Diseases / diagnosis*
Magnetic Resonance Imaging / methods*
Myocardial Contraction*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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