Document Detail


MRI in patients with inflammatory bowel disease.
MedLine Citation:
PMID:  21512607     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Inflammatory bowel disease (IBD) affects ≈1.4 million people in North America and, because of its typical early age of onset and episodic disease course, IBD patients often undergo numerous imaging studies over the course of their lifetimes. Computed tomography (CT) has become the standard imaging modality for assessment of IBD patients because of its widespread availability, rapid image acquisition, and ability to evaluate intraluminal and extraluminal disease. However, repetitive CT imaging has been associated with a significant ionizing radiation risk to patients, making MRI an appealing alternative IBD imaging modality. Pelvic MRI is currently the imaging gold standard for detecting perianal disease, while recent studies indicate that MRI bowel-directed techniques (enteroclysis, enterography, colonography) can accurately evaluate bowel inflammation in IBD. With recent technical innovations leading to faster and higher resolution body MRI, the role of MRI in IBD evaluation is likely to continue to expand. Future applications include surveillance imaging, detection of mural fibrosis, and early assessment of therapy response.
Authors:
Michael S Gee; Mukesh G Harisinghani
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of magnetic resonance imaging : JMRI     Volume:  33     ISSN:  1522-2586     ISO Abbreviation:  J Magn Reson Imaging     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-05-12     Completed Date:  2011-08-09     Revised Date:  2012-03-01    
Medline Journal Info:
Nlm Unique ID:  9105850     Medline TA:  J Magn Reson Imaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  527-34     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Wiley-Liss, Inc.
Affiliation:
Division of Abdominal Imaging and Interventional Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA.
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MeSH Terms
Descriptor/Qualifier:
Colitis, Ulcerative / diagnosis*,  pathology
Contrast Media / pharmacology
Crohn Disease / diagnosis*,  pathology
Diagnostic Imaging / methods*
Fistula / pathology
Gastrointestinal Tract / pathology
Humans
Inflammation
Inflammatory Bowel Diseases / diagnosis,  pathology
Intestine, Small / pathology
Intestines / pathology
Magnetic Resonance Imaging / methods*
Reproducibility of Results
Tomography, X-Ray Computed / methods
Grant Support
ID/Acronym/Agency:
UL1 RR025758-02S2/RR/NCRR NIH HHS
Chemical
Reg. No./Substance:
0/Contrast Media

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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