Document Detail


MRI in diagnosis of orbital masses.
MedLine Citation:
PMID:  20958187     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To evaluate the role of diffusion-weighted magnetic resonance imaging and proton magnetic resonance spectroscopy in diagnosis of different orbital masses and their advantages over conventional magnetic resonance imaging.
METHODS: The study included 32 patients presenting with proptosis. Every patient was subjected to a clinical examination; conventional MRI "T1 weighted, T2 weighted, and post-contrast T1 weighted if needed;" diffusion-weighted MRI; and proton magnetic resonance spectroscopy. Orbitotomy was performed, the orbital mass was excised, and histopathological examination was performed.
RESULTS: Diffusion-weighted MRI can be used to differentiate between benign lesions and malignant tumors in 75% of cases; however, overlap occurred in 25% of cases with benign tumors showing restricted diffusion while proton magnetic resonance spectroscopy could differentiate between benign and malignant tumors in 93.7% of cases.
CONCLUSION: Diffusion-weighted MRI and proton magnetic resonance spectroscopy increased the accuracy of diagnosis of orbital masses through giving in vivo tissue characterization; with magnetic resonance spectroscopy being more accurate.
Authors:
Nader Roshdy; Maha Shahin; Hanem Kishk; Asaad A Ghanem; Sherif El-Khouly; Amany Mousa; Iman Elsalekh
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Current eye research     Volume:  35     ISSN:  1460-2202     ISO Abbreviation:  Curr. Eye Res.     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-10-20     Completed Date:  2011-01-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8104312     Medline TA:  Curr Eye Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  986-91     Citation Subset:  IM    
Affiliation:
Mansoura Ophthamic Center, Mansoura University, Mansoura, Egypt.
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MeSH Terms
Descriptor/Qualifier:
Adenocarcinoma / diagnosis
Adult
Exophthalmos / diagnosis
Eyelid Neoplasms / diagnosis
Female
Humans
Lacrimal Apparatus Diseases / diagnosis
Lymphoma / diagnosis
Magnetic Resonance Imaging*
Male
Meibomian Glands / pathology
Melanoma / diagnosis
Middle Aged
Orbital Neoplasms / diagnosis*,  surgery
Protons
Rhabdomyosarcoma / diagnosis
Chemical
Reg. No./Substance:
0/Protons

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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