| MRI in detection of brain metastases at initial staging of small-cell lung cancer. | |
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MedLine Citation:
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PMID: 8741187 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We prospectively investigated 40 patients with small-cell carcinoma of the lung (SCLC) for signs of brain metastasis by neurological examination and MRI of the brain, to determine the significance of MRI for staging. MRI could not be completed in one patient, who was excluded from the study. The MRI studies of the remaining patients showed no abnormalities in 12, cerebral infarcts in 2 and brain metastases in 11 patients, of whom 3 no relevant symptoms. Nonenhancing white matter lesions were found in 14 patients. In 3 of the 4 patients with an abnormal neurological examination at diagnosis, nonenhancing white matter lesions later developed into contrast enhancing lesions compatible with brain metastases; in 2, this occurred during the course of the chemotherapy. MRI did not change the clinical staging in patients with asymptomatic brain metastases. |
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Authors:
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M van de Pol; A G van Oosterhout; J T Wilmink; G P ten Velde; A Twijnstra |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Neuroradiology Volume: 38 ISSN: 0028-3940 ISO Abbreviation: Neuroradiology Publication Date: 1996 Apr |
Date Detail:
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Created Date: 1996-10-01 Completed Date: 1996-10-01 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 1302751 Medline TA: Neuroradiology Country: GERMANY |
Other Details:
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Languages: eng Pagination: 207-10 Citation Subset: IM |
Affiliation:
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Department of Neurology, University Hospital Maastricht, The Netherlands. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Brain Neoplasms / diagnosis*, secondary* Carcinoma, Small Cell / diagnosis*, secondary* Humans Lung Neoplasms / pathology* Magnetic Resonance Imaging* Middle Aged Neoplasm Staging Prospective Studies |
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