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MRI-guided percutaneous coaxial cutting needle biopsy of small pulmonary nodules: feasibility.
MedLine Citation:
PMID:  23645385     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
OBJECTIVES: To prospectively evaluate the feasibility, safety and accuracy of magnetic resonance imaging (MRI)-guided percutaneous coaxial cutting needle biopsy of small (≤2.0 cm in diameter) pulmonary nodules. METHODS: Ninety-six patients (56 men and 40 women) with 96 small lung nodules underwent MRI-guided percutaneous coaxial cutting needle biopsy. These lesions were divided into two groups according to maximum nodule diameters: 0.5-1.0 cm (n = 25) and 1.1-2.0 cm (n = 71). The diagnostic accuracy, sensitivity and specificity were calculated, and comparison of the two groups was performed using Fisher's exact test. RESULTS: All specimens obtained were sufficient for diagnosis. Histological examination of needle biopsy revealed 64 malignant, 30 benign and 2 indeterminate nodules. The final diagnoses from surgery or clinical follow-up were 67 malignant nodules and 29 benign nodules. The diagnostic performance of MRI-guided percutaneous coaxial cutting needle biopsy in diagnosing malignant tumours was as follows: accuracy, 97 %; sensitivity, 96 %; specificity, 100 %; positive predictive value, 100 %; and negative predictive value, 91 %. There was no significant difference between the two groups (P > 0.05, Fisher's exact test). No serious complications occurred. CONCLUSIONS: MRI-guided percutaneous coaxial cutting needle biopsy is a safe and accurate diagnostic technique in the evaluation of small lung nodules. KEY POINTS: • MRI-guided biopsy helps clinicians to assess patients with small lung nodules. • Differentiation of malignant and benign nodules is possible with 97 % accuracy. • MRI guidance enables accurate lung biopsy without ionising radiation. • No serious complications occurred in MRI-guided lung biopsy.
Authors:
Ming Liu; Yubo Lv; Lebin Wu; Jiqing Song; Roberto Blanco Sequeiros; Chengli Li
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-5-5
Journal Detail:
Title:  European radiology     Volume:  -     ISSN:  1432-1084     ISO Abbreviation:  Eur Radiol     Publication Date:  2013 May 
Date Detail:
Created Date:  2013-5-6     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9114774     Medline TA:  Eur Radiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
From the Department of Interventional MRI, Shandong Medical Imaging Research Institute, Shandong University, Jinan, Shandong, People's Republic of China.
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