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MRI findings of neurological complications in hand-foot-mouth disease by enterovirus 71 infection.
MedLine Citation:
PMID:  22248036     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Abstract Objective To explore the imaging characterization of neurological complications associated with the enterovirus 71 epidemics. Methods 35 cases of hand-foot-mouth disease with neurological complications during the recent EV71 outbreaks of Hainan province China from May 2008 to September 2010 were collected. All patients were performed MRI scan. The clinical data and MRI appearance were analyzed. Results Acute flaccid paralysis associated with enterovirus 71 infected hand- foot-mouth diseases was seen in 7 cases. The typical MRI appearance was linear long T2 signal intensity in the posterior part of spinal cord. Symmetrical, well-defined hyperintensity lesions in the spinal cord were seen in T2-weighted transverse images. Obvious enhancement of the ventral horns and root were seen in the contrast-enhanced axial T1-weighted image. In 21 cases of pontine encephalitis, Long T1 and long T2 signal intensity was seen in the posterior portions of the medulla oblongata, midbrain, and pons. It is nonspecific MRI appearance in 7 cases of aseptic meningitis (AM), but subdural effusion, meningeal enhancement and hydrocephalus can be indirect sigh of AM. Conclusion MRI is an effective modality to investigate neurological complications associated with the enterovirus 71 epidemics. Involvement of Posterior portions of the medulla oblongata and pons, bilateral anterior horns of spinal are characteristic findings.
Authors:
Li Jianjun; Chen Feng; Liu Tao Wang Ling
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-1-17
Journal Detail:
Title:  The International journal of neuroscience     Volume:  -     ISSN:  1563-5279     ISO Abbreviation:  -     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-1-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0270707     Medline TA:  Int J Neurosci     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Radiological department, Renmin Hospital of Hainan Province , 570311.
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