| MRI findings of neuro-Behcet's disease. | |
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MedLine Citation:
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PMID: 21165752 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Neurological manifestations present in 5% to 30% of patients with Behçet's disease. We studied consecutive patients with relapsing-remitting or progressive neuro-Behcet's disease who referred from January 2002 to January 2009 to Nemazee Hospital, Shiraz, southern Iran. Sequential MRIs were performed during clinical relapses in patients with relapsing-remitting course or during relentless progression after first referral of patients with progressive course. We reviewed 55 MRIs of 17 patients (ten men and seven women) with age of 36.4 ± 8.1 years at the time of first MRI. Nine (53%) patients had a relapsing-remitting course and eight (47%) had a progressive course. The initial and last follow-up studies had a mean interval of 29.2 months (range, 24 to 84). Of the patients with progressive neuro-Behcet's disease, 50% had brainstem atrophy and 75% had black holes in their last follow-up MRIs. The respective prevalence rates for those with relapsing-remitting neuro-Behcet's disease were 0% and 11%. In the total population of patients with neuro-Behcet's disease, the number of lesions (p = 0.002) and MRI burden (p = 0.016) had a significant increase in the last follow-up studies in comparison to the initial studies. Incremental pattern in the number of lesions and MRI burdens in patients with parenchymal neuro-Behcet's disease in our longitudinal study may imply an ongoing pathologic process. |
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Authors:
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Afshin Borhani Haghighi; Sirous Sarhadi; Siamak Farahangiz |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2010-12-18 |
Journal Detail:
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Title: Clinical rheumatology Volume: - ISSN: 1434-9949 ISO Abbreviation: - Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-12-17 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8211469 Medline TA: Clin Rheumatol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Transgenic Technology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran, borhanihaghighi@yahoo.com. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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