Document Detail


MRI findings in macrocephaly-cutis marmorata telangiectatica congenita.
MedLine Citation:
PMID:  9511980     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We describe a child with macrocephaly-cutis marmorata telangiectatica congenita (M-CMTC), cherry red macules, megalencephaly with hemifacial and segmental overgrowth, macrosomia, and cutis marmorata telangiectasia congenita of the trunk, and visceral and subcutaneous cavernous hemangiomas. The megalencephaly is accompanied by MRI findings of CNS dysgenesis with protrusion of the cerebellar tonsils through the foramen magnum (Chiari I), lumbar syrinx, and hydrops of the optic nerves. The report of this additional patient further confirms the newly described macrocephaly-cutis marmorata telangiectatica congenita as a distinct clinical phenotype.
Authors:
M Carcao; S I Blaser; R M Grant; R Weksberg; J Siegel-Bartelt
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  American journal of medical genetics     Volume:  76     ISSN:  0148-7299     ISO Abbreviation:  Am. J. Med. Genet.     Publication Date:  1998 Mar 
Date Detail:
Created Date:  1998-05-14     Completed Date:  1998-05-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7708900     Medline TA:  Am J Med Genet     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  165-7     Citation Subset:  IM    
Affiliation:
Department of Paediatrics, Hospital for Sick Children, Toronto, Ontario, Canada.
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MeSH Terms
Descriptor/Qualifier:
Abnormalities, Multiple / diagnosis*,  pathology
Birth Weight
Brain / abnormalities
Craniofacial Abnormalities / diagnosis*,  pathology
Fetal Macrosomia / complications
Humans
Infant
Magnetic Resonance Imaging
Male
Syndrome
Telangiectasis / diagnosis,  pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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