Document Detail


MRI findings of hypoxic cortical laminar necrosis in a child with hemolytic anemia crisis.
MedLine Citation:
PMID:  16440236     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We present magnetic resonance imaging findings of a 5-year-old girl who had a rapidly installing hemolytic anemia crisis induced by trimethoprim-sulfomethoxazole, resulting in cerebral anoxia leading to permanent damage. Magnetic Resonance imaging revealed cortical laminar necrosis in arterial border zones in both cerebral hemispheres, ischemic changes in subcortical white matter of left cerebral hemisphere, and in the left putamen. Although cortical laminar necrosis is a classic entity in adulthood related to conditions of energy depletions, there are few reports available in children. A wide review of the literature is also presented.
Authors:
Osman Kizilkilic; Sait Albayram; Ozgür Kasapcopur; Ismail Mihmanli; Naci Kocer; Civan Islak
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Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2002-11-22
Journal Detail:
Title:  European radiology     Volume:  13 Suppl 6     ISSN:  1432-1084     ISO Abbreviation:  Eur Radiol     Publication Date:  2003 Dec 
Date Detail:
Created Date:  2006-01-27     Completed Date:  2009-03-31     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9114774     Medline TA:  Eur Radiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  L133-7     Citation Subset:  IM    
Affiliation:
Department of Radiology, Division of Neuroradiology, Cerrahpasa Medical Faculty, 34300 Istanbul, Turkey.
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MeSH Terms
Descriptor/Qualifier:
Anemia, Hemolytic / chemically induced,  complications*
Anti-Infective Agents / adverse effects
Arnold-Chiari Malformation / diagnosis
Brain Ischemia / diagnosis,  etiology
Cerebral Cortex / pathology
Child, Preschool
Epilepsy, Tonic-Clonic / etiology
Female
Humans
Hypoxia, Brain / diagnosis,  etiology*
Magnetic Resonance Imaging*
Necrosis
Putamen / pathology
Tomography, X-Ray Computed
Trimethoprim-Sulfamethoxazole Combination / adverse effects
Chemical
Reg. No./Substance:
0/Anti-Infective Agents; 8064-90-2/Trimethoprim-Sulfamethoxazole Combination

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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