Document Detail


MRI analysis of in vivo meniscal and tibiofemoral kinematics in ACL-deficient and normal knees.
MedLine Citation:
PMID:  16652339     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The objectives of this study were to analyze simultaneously meniscal and tibiofemoral kinematics in healthy volunteers and anterior cruciate ligament (ACL)-deficient patients under axial load-bearing conditions using magnetic resonance imaging (MRI). Ten healthy volunteers and eight ACL-deficient patients were examined with a high-field, closed MRI system. For each group, both knees were imaged at full extension and partial flexion ( approximately 45 degrees ) with a 125N compressive load applied to the foot. Anteroposterior and medial/lateral femoral and meniscal translations were analyzed following three-dimensional, landmark-matching registration. Interobserver and intraobserver reproducibilities were less than 0.8 mm for femoral translation for image processing and data analysis. The position of the femur relative to the tibia in the ACL-deficient knee was 2.6 mm posterior to that of the contralateral, normal knee at extension. During flexion from 0 degrees to 45 degrees , the femur in ACL-deficient knees translated 4.3 mm anteriorly, whereas no significant translation occurred in uninjured knees. The contact area centroid on the tibia in ACL-deficient knees at extension was posterior to that of uninjured knees. Consequently, significantly less posterior translation of the contact centroid occurred in the medial tibial condyle in ACL-deficient knees during flexion. Meniscal translation, however, was nearly the same in both groups. Axial load-bearing MRI is a noninvasive and reproducible method for evaluating tibiofemoral and meniscal kinematics. The results demonstrated that ACL deficiency led to significant changes in bone kinematics, but negligible changes in the movement of the menisci. These results help explain the increased risk of meniscal tears and osteoarthritis in chronic ACL deficient knees.
Authors:
Sandra J Shefelbine; C Benjamin Ma; Keh-Yang Lee; Mark A Schrumpf; Priyesh Patel; Marc R Safran; John P Slavinsky; Sharmila Majumdar
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of orthopaedic research : official publication of the Orthopaedic Research Society     Volume:  24     ISSN:  0736-0266     ISO Abbreviation:  J. Orthop. Res.     Publication Date:  2006 Jun 
Date Detail:
Created Date:  2006-05-22     Completed Date:  2006-06-29     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8404726     Medline TA:  J Orthop Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1208-17     Citation Subset:  IM    
Copyright Information:
(c) 2006 Orthopaedic Research Society. Published by Wiley Periodicals, Inc.
Affiliation:
Department of Orthopaedic Surgery, University of California, San Francisco, 500 Parnassus Avenue, MU 320W, San Francisco, California 94143-0728, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Anterior Cruciate Ligament / injuries,  pathology
Biomechanics
Femur / pathology,  physiopathology*
Humans
Joint Instability / pathology,  physiopathology
Knee Joint / pathology,  physiopathology*
Magnetic Resonance Imaging / methods*
Menisci, Tibial / pathology,  physiopathology*
Observer Variation
Range of Motion, Articular*
Reproducibility of Results
Tibia / pathology,  physiopathology*
Weight-Bearing
Grant Support
ID/Acronym/Agency:
R01AR17762/AR/NIAMS NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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