Document Detail

MRI and PET-CT in the diagnosis and follow-up of a lymphoma case with multifocal peripheral nerve involvement.
MedLine Citation:
PMID:  23255069     Owner:  NLM     Status:  Publisher    
Lymphoma of the peripheral nerve, particularly of the T-cell variety, is an extremely rare subtype of extra nodal lymphoma that has a variable response to current therapeutic regimens. Here, we present a patient with natural killer (NK)/T-cell lym- phoma in remission who presented with a two-month history of right forearm swelling and paresthesia in the ulnar nerve distribution. Magnetic resonance imaging (MRI) showed an ulnar nerve mass identified as a nerve sheath tumor. Frozen section and post-resection biopsies showed an Epstein-Barr virus-positive NK/T-cell lymphoma, nasal type. Consequently, the patient received chemotherapy following resection. Four months later, the patient developed a proximal leg mass, which was diagnosed as tibial nerve lymphoma. The patient was then treated with chemotherapy and follow-up was done by positron emission tomography-computed tomogra- phy (PET-CT). In conclusion, lymphoma should be consid- ered in the differential diagnosis of a peripheral nerve mass. MRI is a useful imaging tool together with PET-CT, which plays a beneficial role in the follow-up of these patients on therapy as well as diagnosis of new lesions.
Sachin Agrawal; Ming Tye Gi; Siok Bian Ng; Mark Edward Puhaindran; Poonam Singhania
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-12-13
Journal Detail:
Title:  Diagnostic and interventional radiology (Ankara, Turkey)     Volume:  -     ISSN:  1305-3612     ISO Abbreviation:  Diagn Interv Radiol     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101241152     Medline TA:  Diagn Interv Radiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Diagnostic Imaging, National University Hospital, Singapore, Singapore.
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