| MRI may be sufficient for noninvasive assessment of great vessel stents: an in vitro comparison of MRI, CT, and conventional angiography. | |
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MedLine Citation:
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PMID: 20858811 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The purpose of this study was to compare the diagnostic performance of MRI and CT assessment of great vessel stents in an in vitro model. MATERIALS AND METHODS: Three contemporary great vessel stent materials (nitinol, platinum-iridium, and stainless steel) were assessed with three luminal conditions: no stenosis, internal stenosis, and external stenosis. Stents of the same material were implanted into an aorta model that was attached to an animal bypass pump with pulsatile flow. Each stent was imaged with conventional angiography as reference standard, 10 different MRI sequences, and CT. The sensitivity and specificity for the identification of stent stenosis was determined and stent lumen measurements compared. RESULTS: Of the investigated MRI sequences, three had the highest overall sensitivity and specificity for the identification of stent stenosis in all studied materials: through-plane gradientrecalled echo (GRE) with 75° flip angle (100% and 95%, respectively), in- and through-plane steady-state free precession (SSFP) (99% and 90%) and MR angiography (MRA) with 75° flip angle (93% and 85%). Comparable sensitivity and specificity were achieved with CT (98% and 93%). GRE, SSFP, and MRA sequences tended to underestimate stent lumen diameter in externally nonstenosed stents and overestimate diameter in internally stenosed stents (p < 0.05). CT slightly underestimated external stenoses in all stent types (p < 0.05). CONCLUSION: Defined MRI sequences are feasible to assess nitinol, platinum-iridium, and stainless steel great vessel stents with diagnostic performance comparable with CT. |
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Authors:
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Johannes Nordmeyer; Régis Gaudin; Oliver R Tann; Phillip C Lurz; Phillip Bonhoeffer; Andrew M Taylor; Vivek Muthurangu |
Publication Detail:
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Type: Comparative Study; In Vitro; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: AJR. American journal of roentgenology Volume: 195 ISSN: 1546-3141 ISO Abbreviation: AJR Am J Roentgenol Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-09-22 Completed Date: 2010-10-29 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7708173 Medline TA: AJR Am J Roentgenol Country: United States |
Other Details:
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Languages: eng Pagination: 865-71 Citation Subset: AIM; IM |
Affiliation:
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Cardiorespiratory Unit, Great Ormond Street Hospital for Children, NHS Trust, London WC1N 3JH, United Kingdom. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Angiography
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methods* Animals Aorta Magnetic Resonance Imaging* Sensitivity and Specificity Stents* Swine Tomography, X-Ray Computed* |
| Grant Support | |
ID/Acronym/Agency:
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CI/05/010//British Heart Foundation; FS/08/012/24454//British Heart Foundation |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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