| MRI and CT findings of neurohypophyseal germinoma. | |
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MedLine Citation:
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PMID: 14962649 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: Magnetic resonance (MR) imaging and computed tomography (CT) findings of neurohypophyseal germinoma have not previously been described in detail. The purpose of the present study was to establish the spectrum of MR imaging and CT findings in neurohypophyseal germinomas. MATERIALS AND METHODS: MR and CT images of 13 consecutive patients (seven males, six females; mean age: 15 years; range: 6-31 years) with neurohypophyseal germinoma were retrospectively analyzed. The diagnosis had been made either histologically (n=8) or clinically according to established criteria (n=5). All patients had been examined using MR imaging and CT before treatment. RESULTS: On MR imaging, infundibular thickening (up to 16 mm) was observed in all 13 cases. Hyperintensity of the posterior pituitary on T1-weighted image was absent in all 13 cases (100%) and 12 of the 13 displayed central diabetes insipidus. Ten germinomas (77%) were isointense to cerebral cortex on T1-weighted image, but variable intensities were exhibited on T2-weighted image. MR images revealed intratumoral cysts in six cases (46%), most of which demonstrated intra-third ventricular extension. Eleven of the 13 cases (85%) revealed hyperdense solid components on unenhanced CT. Calcification was absent in all cases (100%). CONCLUSION: Infundibular thickening, absence of the posterior pituitary high signal on T1-weighted image, lack of calcification and hyperdensity on unenhanced CT are common imaging features of neurohypophyseal germinoma. |
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Authors:
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Mitsunori Kanagaki; Yukio Miki; Jun A Takahashi; Yuta Shibamoto; Takahiro Takahashi; Tetsuya Ueba; Nobuo Hashimoto; Junji Konishi |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: European journal of radiology Volume: 49 ISSN: 0720-048X ISO Abbreviation: Eur J Radiol Publication Date: 2004 Mar |
Date Detail:
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Created Date: 2004-02-13 Completed Date: 2005-03-15 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8106411 Medline TA: Eur J Radiol Country: Ireland |
Other Details:
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Languages: eng Pagination: 204-11 Citation Subset: IM |
Affiliation:
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Department of Nuclear Medicine and Diagnostic Imaging, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Child Contrast Media / administration & dosage Diabetes Insipidus, Neurogenic / complications Female Gadolinium DTPA / diagnostic use Germinoma / complications, diagnosis* Humans Magnetic Resonance Imaging / methods* Male Pituitary Gland / pathology*, radiography* Pituitary Neoplasms / complications, diagnosis* Retrospective Studies Tomography, X-Ray Computed / methods* |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 122795-43-1/gadodiamide; 80529-93-7/Gadolinium DTPA |
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