| MR perfusion imaging in proliferative angiopathy. | |
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MedLine Citation:
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PMID: 14726982 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Seizures, which may be the main expression of cerebral arteriovenous malformations (CAVM) can be difficult to control medically. Our goal was to use perfusion-weighted imaging (PWI) in correlation with clinical data to detect abnormal areas of the cerebrum related to a particular type of CAVM (proliferative angiopathy) and to study the pathophysiology. We use PWI, with a bolus injection of contrast medium, to investigate seven patients with proliferative angiopathy and fits producing language disturbance. Perfusion parameters were calculated using the first-pass moment theory. Five patients had perimalformative and/or contralateral abnormal areas with relative hyperperfusion (cerebral blood volume +20.7+/-16.2%, blood flow 92.5+/-68.8 ml/min/100 g). Areas of hypoperfusion and venous congestion were detected in two patients. One patient who underwent MRI after a severe focal deficit had no significant haemodynamic abnormality. |
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Authors:
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D Ducreux; J F Meder; D Fredy; J Bittoun; P Lasjaunias |
Publication Detail:
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Type: Comparative Study; Journal Article Date: 2004-01-16 |
Journal Detail:
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Title: Neuroradiology Volume: 46 ISSN: 0028-3940 ISO Abbreviation: Neuroradiology Publication Date: 2004 Feb |
Date Detail:
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Created Date: 2004-03-01 Completed Date: 2004-07-07 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 1302751 Medline TA: Neuroradiology Country: Germany |
Other Details:
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Languages: eng Pagination: 105-12 Citation Subset: IM |
Affiliation:
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Neuroradiology Department, CHU de Bicêtre, Paris XI University, 78 rue du Gènèral Leclerc, 94270, Le Kremlin Bicêtre, France. denis.ducreux@bct.ap-hop-paris.fr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Blood Flow Velocity / physiology Blood Volume / physiology Brain Ischemia / diagnosis Carotid Artery, Internal / abnormalities, pathology Cerebellum / blood supply Cerebral Cortex / blood supply Contrast Media / administration & dosage Deglutition Disorders / etiology Diagnosis, Differential Dominance, Cerebral / physiology Embolization, Therapeutic Epilepsy / etiology* Female Follow-Up Studies Fourier Analysis Gadolinium DTPA / diagnostic use Humans Image Enhancement* Image Processing, Computer-Assisted* Intracranial Arteriovenous Malformations / diagnosis*, therapy Magnetic Resonance Angiography* Male Middle Aged Regional Blood Flow / physiology Sensitivity and Specificity |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 80529-93-7/Gadolinium DTPA |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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