| MR motility imaging in Crohn's disease improves lesion detection compared with standard MR imaging. | |
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MedLine Citation:
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PMID: 20379822 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To evaluate retrospectively in patients with Crohn's disease (CD) if magnetic resonance (MR) motility alterations correlate with CD typical lesions leading to an increased detection rate. METHODS: Forty patients with histologically proven CD underwent MR enterography (MRE), including coronal cine sequences (cine MRE), in addition to the standard CD MR protocol. Two blinded readings were performed with and without cine MRE. Locations presenting motility alterations on the cine sequences were analysed on standard MRE for CD-related lesions. This was compared with a second reading using the standard clinical MRE protocol alone. RESULTS: The number of lesions localised by cine MRE and identified on standard MRE compared with standard MRE alone were 35/24 for wall thickening (p = 0.002), 24/20 for stenoses (p = 0.05), 17/11 for wall layering (p = 0.02), 5/3 for mucosal ulcers (p = 0.02) and 21/17 for the comb sign (p = 0.05). Overall, cine MRE detected 35 more CD-specific findings than standard MRE alone (124/89; p = 0.007) and significantly more patients with CD-relevant MR findings (34/28; p = 0.03). CONCLUSION: CD lesions seem to be associated with motility changes and this leads to an increased lesion detection rate compared with standard-MRE imaging alone. |
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Authors:
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Johannes M Froehlich; Christian Waldherr; Christoforos Stoupis; S Mehmet Erturk; Michael A Patak |
Publication Detail:
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Type: Comparative Study; Evaluation Studies; Journal Article Date: 2010-04-09 |
Journal Detail:
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Title: European radiology Volume: 20 ISSN: 1432-1084 ISO Abbreviation: Eur Radiol Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-07-08 Completed Date: 2010-11-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9114774 Medline TA: Eur Radiol Country: Germany |
Other Details:
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Languages: eng Pagination: 1945-51 Citation Subset: IM |
Affiliation:
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Institute of Diagnostic, Interventional and Pediatric, Radiology, Inselspital, University Hospital, Bern, Switzerland. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Crohn Disease / diagnosis* Female Gastrointestinal Motility* Humans Image Enhancement / methods* Intestines / pathology* Magnetic Resonance Imaging, Cine / methods* Male Middle Aged Reproducibility of Results Sensitivity and Specificity Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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