Document Detail

MR imaging of intradural inflammatory diseases of the spine.
MedLine Citation:
PMID:  1950896     Owner:  NLM     Status:  MEDLINE    
Twenty-eight patients with intradural inflammatory disease of the spine were studied in order to characterize the MR imaging findings of infectious and inflammatory conditions. Patients were categorized according to the spinal compartment involved. Among the 12 patients in the intradural extramedullary group, unenhanced scans were either normal or nonspecific while contrast-enhanced scans were helpful in visualizing and localizing the lesion. Nevertheless, contrast-enhanced MR studies were unable to differentiate infection and inflammation from tumor in this compartment. Among 16 patients with intramedullary lesions, four had granulomatous disease and 12 had nongranulomatous disease. The granulomatous lesions resembled tumors and displayed MR characteristics of a focal lesion with large nodular enhancement. The patients with nongranulomatous intramedullary lesions exhibited two subsets of MR findings. In the first subset of nine patients, diffuse cord swelling and high signal were seen on long TR images, combined with either no enhancement or peripheral, diffuse, or speckled enhancement of the spinal cord on contrast-enhanced short TR images. In the second subset of three patients, minimal or no spinal cord swelling was displayed despite the visualization of high signal on long TR scans and nodular enhancement with contrast administration on short TR scans. Both subsets were sufficiently unique that nongranulomatous myelitis could usually be differentiated from spinal cord tumors.
B Gero; G Sze; H Sharif
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  AJNR. American journal of neuroradiology     Volume:  12     ISSN:  0195-6108     ISO Abbreviation:  AJNR Am J Neuroradiol     Publication Date:    1991 Sep-Oct
Date Detail:
Created Date:  1991-12-17     Completed Date:  1991-12-17     Revised Date:  2008-02-14    
Medline Journal Info:
Nlm Unique ID:  8003708     Medline TA:  AJNR Am J Neuroradiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1009-19     Citation Subset:  IM    
Department of Diagnostic Radiology, Yale University School of Medicine, New Haven, CT 06510.
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MeSH Terms
Dura Mater / pathology*
Image Enhancement
Inflammation / diagnosis
Magnetic Resonance Imaging*
Medulla Oblongata / pathology
Spinal Cord Diseases / diagnosis*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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