Document Detail


MR imaging of hemorrhagic conditions of the head and neck.
MedLine Citation:
PMID:  3380990     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
1. There is a constant sequence of signal intensity patterns that characterize 1.5 T, spin echo MR images of hemorrhagic lesions. 2. The MRI appearance of intraparenchymal hemorrhage is determined by the sequential chemical degradation of Hb, by the paramagnetic properties of the degradation products and by certain biologic factors including pO2, edema formation, hematocrit and BBB. 3. Acute intraparenchymal hemorrhage is characterized by markedly diminished signal intensity centrally relative to surrounding white matter (hypointensity) on T2 weighted images and often by a moderately increased signal intensity (hyperintensity) of the adjacent white matter produced by surrounding edema on proton density and T2 weighted images. 4. Early subacute intraparenchymal hemorrhage is characterized centrally by moderate hypointensity on T2 weighted images, and peripherally, by moderate hyperintensity on T1 weighted and marked hypointensity on T2 weighted images. Hyperintensity on proton density and T2 weighted images of nearby white matter owing to edema may again be seen. 5. Late subacute intraparenchymal hemorrhage is characterized by marked peripheral and central hyperintensity on both T1 and T2 weighted images. Also, marked hypointensity of the adjacent brain rim on T2 weighted images owing to hemosiderin deposition may be seen. 6. Chronic intraparenchymal hemorrhage is characterized by marked hyperintensity both centrally and peripherally on both T1 and T2 weighted images and by marked hypointensity of the adjacent brain rim on T2 weighted images owing to hemosiderin deposition. Surrounding edema is no longer present. 7. The integrity of the blood-brain barrier appears to be important in determining whether or not hemosiderin accumulations consistently occur in subacute and chronic hemorrhage. 8. Hemorrhagic conditions in which the defined sequence of signal intensity patterns may be seen include: venous thrombosis, hemorrhagic infarction, occult vascular malformation and intracranial aneurysm.
Authors:
R I Grossman; J M Gomori; H I Goldberg; D B Hackney; S W Atlas; S S Kemp; R A Zimmerman; L T Bilaniuk
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Radiographics : a review publication of the Radiological Society of North America, Inc     Volume:  8     ISSN:  0271-5333     ISO Abbreviation:  Radiographics     Publication Date:  1988 May 
Date Detail:
Created Date:  1988-07-25     Completed Date:  1988-07-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8302501     Medline TA:  Radiographics     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  441-54     Citation Subset:  IM    
Affiliation:
Department of Radiology, Hospital of the University of Pennsylvania 19104.
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Adult
Blood-Brain Barrier
Brain / pathology
Cerebral Hemorrhage / blood,  diagnosis*,  physiopathology
Cerebral Infarction / diagnosis
Chronic Disease
Hematocrit
Hematoma / diagnosis
Humans
Intracranial Aneurysm / diagnosis
Intracranial Arteriovenous Malformations / diagnosis
Intracranial Embolism and Thrombosis / diagnosis
Magnetic Resonance Imaging*
Oxyhemoglobins / metabolism
Chemical
Reg. No./Substance:
0/Oxyhemoglobins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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