Document Detail


MR imaging of the breast with Gd-DTPA: use and limitations.
MedLine Citation:
PMID:  2648479     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Between August 1985 and November 1987, 150 patients with 167 biopsy-proved lesions were examined with magnetic resonance (MR) imaging enhanced with gadolinium diethylenetriaminepentaacetic acid, mammography, and palpation. Of these patients, 113 with 123 lesions were also examined with ultrasound. Enhancement above 300 normalized units (NU) on MR images was considered significant; between 250 and 300 NU, borderline; and below 250, nonsignificant. All 27 fibroadenomas and 70 of 71 carcinomas showed significant enhancement; one carcinoma showed borderline enhancement. Nonproliferative dysplasia showed nonsignificant enhancement in 15 of 16 cases and significant enhancement in one, whereas proliferative dysplasia showed usually diffuse enhancement varying from nonsignificant (five of 30 cases) to borderline (five of 30 cases) to significant (20 of 30 cases). In the nonblind evaluation of the modalities, MR imaging compared favorably. When limitations of the technique were considered, MR imaging seemed beneficial as a supplement in selected, diagnostically difficult cases.
Authors:
S H Heywang; A Wolf; E Pruss; T Hilbertz; W Eiermann; W Permanetter
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Radiology     Volume:  171     ISSN:  0033-8419     ISO Abbreviation:  Radiology     Publication Date:  1989 Apr 
Date Detail:
Created Date:  1989-04-28     Completed Date:  1989-04-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  95-103     Citation Subset:  AIM; IM    
Affiliation:
Department of Radiology, Klinikum Grosshadern, University of Munich, Federal Republic of Germany.
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MeSH Terms
Descriptor/Qualifier:
Adenofibroma / diagnosis
Breast Neoplasms / diagnosis*
Carcinoma / diagnosis
Contrast Media*
Female
Gadolinium / diagnostic use*
Gadolinium DTPA
Humans
Magnetic Resonance Imaging*
Mammography
Organometallic Compounds / diagnostic use*
Palpation
Pentetic Acid / diagnostic use*
Prospective Studies
Ultrasonography
Chemical
Reg. No./Substance:
0/Contrast Media; 0/Organometallic Compounds; 67-43-6/Pentetic Acid; 7440-54-2/Gadolinium; 80529-93-7/Gadolinium DTPA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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