Document Detail


MR findings after depth electrode implantation for medically refractory epilepsy.
MedLine Citation:
PMID:  8279329     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To evaluate using MR imaging chronic changes in the brain parenchyma after electroencephalography depth electrode placement in patients with medically refractory epilepsy. METHODS: A retrospective review of MR scans in 57 patients who underwent stereotactic placement of 210 depth electrodes was performed. Scans were evaluated for evidence of gliosis, hemorrhage, or infection along the probe tracts. RESULTS: Signal abnormalities along the probe tracts were seen in 38 patients (67%). Of the 210 probe tracts evaluated on long-repetition-time images, 85 (41%) were associated with punctate hyperintensity and four (2%) with punctate hypointensity; 120 (57%) showed no MR changes to suggest prior electrode placement. One probe placement was complicated by a significant intraparenchymal hemorrhage. CONCLUSIONS: Depth electrode implantation for electroencephalography monitoring results in imperceptible or minimal chronic changes as detected by MR in almost all patients. The punctate hypersensitivity on long-repetition-time images is though to be caused by gliosis along the probe tracts. These signal changes should not be confused with the seizure focus. Significant hemorrhage or infection is a rare complication of probe placement. Incorporation of MR angiographic data with conventional spin-echo images at the time of stereotactic probe placement may further reduce the low incidence of probe-related hemorrhage.
Authors:
M A Merriam; R A Bronen; D D Spencer; G McCarthy
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  AJNR. American journal of neuroradiology     Volume:  14     ISSN:  0195-6108     ISO Abbreviation:  AJNR Am J Neuroradiol     Publication Date:    1993 Nov-Dec
Date Detail:
Created Date:  1994-02-10     Completed Date:  1994-02-10     Revised Date:  2008-02-14    
Medline Journal Info:
Nlm Unique ID:  8003708     Medline TA:  AJNR Am J Neuroradiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1343-6     Citation Subset:  IM    
Affiliation:
Department of Diagnostic Radiology, Yale University School of Medicine, New Haven, CT 06510.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Brain / pathology*
Electrodes, Implanted*
Electroencephalography*
Epilepsy / diagnosis*,  pathology
Female
Humans
Male
Middle Aged
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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