Document Detail


MR features of the developing perianterior horn structure including subcallosal fasciculus in infants and children.
MedLine Citation:
PMID:  17619869     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
INTRODUCTION: To describe the changes in the magnetic resonance (MR) signal of the perianterior horn structure (PAS) with increasing age, we studied 69 infants and children aged between 3 days and 9.4 years (average: 2.8 years) without any neurological deficits. METHODS: T1- and T2-weighted images and FLAIR (fluid attenuation inversion recovery) images were obtained in the axial plane. Based on a comparison of the intensity of the PAS with that of the cortex in each sequence (T1-WI/FLAIR/T2-WI), we classified the signal-intensity patterns into four types: I, low/low/high; II, low/high/high; III, iso/high/high; IV, high/low/low. RESULTS: Signal-intensity types I, II, III and IV were seen in 22, 8, 17, and 22 subjects, respectively, with younger subjects showing type I or II intensity patterns and older subjects showing type III or IV. In addition, T1-weighted and FLAIR images of subjects with a type I intensity pattern showed a rim of an isointensity component around the PAS that histologically coincided with migrating glial cells. The low-intensity area on FLAIR and T2-WI images of subjects with a type IV intensity pattern may represent myelinated fibers of the subcallosal fasciculus (ScF). CONCLUSION: The intensity of the MR signals of the PAS changes with increasing age, and this change may reflect histological features. A better understanding of these characteristics may help us to clarify myelination abnormalities, particularly those related to the ScF in the frontal lobe in infants and children.
Authors:
Hidetsuna Utsunomiya; Yasuhiro Nakamura
Publication Detail:
Type:  Journal Article     Date:  2007-07-10
Journal Detail:
Title:  Neuroradiology     Volume:  49     ISSN:  0028-3940     ISO Abbreviation:  Neuroradiology     Publication Date:  2007 Nov 
Date Detail:
Created Date:  2007-10-25     Completed Date:  2008-03-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  1302751     Medline TA:  Neuroradiology     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  947-54     Citation Subset:  IM    
Affiliation:
Department of Diagnostic Radiology, Fukuoka University School of Medicine, 7-45-1, Nanakuma, Fukuoka, 814-0180, Japan. hide-uts@fukuoka-u.ac.jp
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MeSH Terms
Descriptor/Qualifier:
Age Factors
Child
Child Development / physiology*
Child, Preschool
Corpus Callosum / anatomy & histology*,  growth & development
Female
Frontal Lobe / anatomy & histology,  growth & development
Humans
Infant
Infant, Newborn
Lateral Ventricles / anatomy & histology*,  growth & development*
Magnetic Resonance Imaging*
Male
Perforant Pathway / anatomy & histology*,  growth & development
Reference Values

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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