Document Detail

MR evaluation of cervical cancer in hysterectomy specimens: correlation of quantitative T2 measurement and histology.
MedLine Citation:
PMID:  7865937     Owner:  NLM     Status:  MEDLINE    
Specimens from modified radical hysterectomies performed for invasive carcinoma of the cervix were analyzed with quantitative T2 magnetic resonance (MR) imaging and histologic study to determine to what degree there was a correlation between the findings of the two modalities. The mean T2 of cervical stroma was 48 msec, while the outer zone of the cervix had a mean T2 of 62 msec and the central canal region typically had T2 values of 115 msec +/- 20 (standard deviation). A total of nine cervical cancers were analyzed, and their mean T2 value was 79 msec. Separation between cervical stroma and tumor was good, with stromal T2 values ranging from 30 to 66 msec, while tumor T2s ranged from 60 to 97 msec. Statistical analysis indicated that these data were associated with a sensitivity of 89% and a specificity of 95%, with 95% confidence intervals of [50%, 99.4%] and [74%, 99.7%], respectively, for separating tumor from stroma on the basis of T2 value. Quantitative T2 imaging was found to provide an effective, nonsubjective means of classifying cervical anatomy and neoplastic disease.
A J Martin; C S Poon; G M Thomas; L R Kapusta; P A Shaw; R M Henkelman
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of magnetic resonance imaging : JMRI     Volume:  4     ISSN:  1053-1807     ISO Abbreviation:  J Magn Reson Imaging     Publication Date:    1994 Nov-Dec
Date Detail:
Created Date:  1995-03-28     Completed Date:  1995-03-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9105850     Medline TA:  J Magn Reson Imaging     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  779-86     Citation Subset:  IM    
Sunnybrook Health Science Centre, Toronto Bayview Regional Cancer Centre, Ontario, Canada.
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MeSH Terms
Adenocarcinoma / pathology*,  surgery
Carcinoma, Squamous Cell / pathology*,  surgery
Cervix Mucus
Cervix Uteri / pathology,  surgery
Cysts / pathology
Image Enhancement
Leiomyoma / pathology
Magnetic Resonance Imaging* / statistics & numerical data
Middle Aged
Mucous Membrane / pathology
Neoplasm Invasiveness
Sensitivity and Specificity
Uterine Cervical Neoplasms / pathology*,  surgery

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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