| MR elastography of the in vivo abdominal aorta: a feasibility study for comparing aortic stiffness between hypertensives and normotensives. | |
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MedLine Citation:
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PMID: 22045617 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To demonstrate feasibility of using MR elastography (MRE) to identify hypertensive changes in the abdominal aorta when compared with normotensives based on the stiffness measurements. MATERIALS AND METHODS: MRE was performed on eight volunteers (four normotensives and four hypertensives) to measure the effective stiffness of the abdominal aorta. MRE wave images are directionally filtered and phase gradient analysis was performed to determine the stiffness of the aorta. Student's t-test was performed to determine significant difference in stiffness measurements between normotensives and hypertensives. RESULTS: The normotensive group demonstrated a mean abdominal aortic stiffness of 3.7 ± 0.8 kPa, while the controlled-hypertensive demonstrated a mean abdominal aortic stiffness of 9.3 ± 1.9 kPa. MRE effective stiffness of abdominal aorta in hypertensives was significantly greater than that of normotensives with p = 0.02. CONCLUSION: Feasibility of in vivo aortic MRE is demonstrated. Hypertensives have significantly higher aortic stiffness assessed through MRE than normotensives. |
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Authors:
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Arunark Kolipaka; David Woodrum; Philip A Araoz; Richard L Ehman |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't Date: 2011-11-01 |
Journal Detail:
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Title: Journal of magnetic resonance imaging : JMRI Volume: 35 ISSN: 1522-2586 ISO Abbreviation: J Magn Reson Imaging Publication Date: 2012 Mar |
Date Detail:
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Created Date: 2012-02-15 Completed Date: 2012-06-19 Revised Date: 2013-04-15 |
Medline Journal Info:
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Nlm Unique ID: 9105850 Medline TA: J Magn Reson Imaging Country: United States |
Other Details:
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Languages: eng Pagination: 582-6 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 Wiley Periodicals, Inc. |
Affiliation:
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Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aorta, Abdominal / physiopathology* Case-Control Studies Elasticity Imaging Techniques / methods* Feasibility Studies Female Humans Hypertension / physiopathology* Image Enhancement / methods Image Interpretation, Computer-Assisted Magnetic Resonance Imaging / methods* Male Middle Aged |
| Grant Support | |
ID/Acronym/Agency:
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EB001981/EB/NIBIB NIH HHS; R01 EB001981/EB/NIBIB NIH HHS; R01 EB001981-13/EB/NIBIB NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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