Document Detail


MR compatible positioning device for guiding a focused ultrasound system for the treatment of brain deseases.
MedLine Citation:
PMID:  23744569     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: A prototype magnetic resonance imaging (MRI)-compatible positioning device that navigates a high intensity focused ultrasound (HIFU) transducer is presented. The positioning device has three user-controlled degrees of freedom that allow access to brain targets using a lateral coupling approach. The positioning device can be used for the treatment of brain cancer (thermal mode ultrasound) or ischemic stroke (mechanical mode ultrasound). MATERIALS AND METHODS: The positioning device incorporates only MRI compatible materials such as piezoelectric motors, ABS plastic, brass screws, and brass rack and pinion. RESULT: The robot has the ability to accurately move the transducer thus creating overlapping lesions in rabbit brain in vivo. The registration and repeatability of the system was evaluated using tissues in vitro and gel phantom and was also tested in vivo in the brain of a rabbit. CONCLUSION: A simple, cost effective, portable positioning device has been developed which can be used in virtually any clinical MRI scanner since it can be placed on the table of the MRI scanner. This system can be used to treat in the future patients with brain cancer and ischemic stroke. Copyright © 2013 John Wiley & Sons, Ltd.
Authors:
N Mylonas; C Damianou
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-6-7
Journal Detail:
Title:  The international journal of medical robotics + computer assisted surgery : MRCAS     Volume:  -     ISSN:  1478-596X     ISO Abbreviation:  Int J Med Robot     Publication Date:  2013 Jun 
Date Detail:
Created Date:  2013-6-7     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101250764     Medline TA:  Int J Med Robot     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2013 John Wiley & Sons, Ltd.
Affiliation:
City University, London, UK; Frederick Institute of Technology, Limassol, Cyprus.
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