| An MR-compatible bicycle ergometer for in-magnet whole-body human exercise testing. | |
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MedLine Citation:
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PMID: 19918886 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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An MR-compatible ergometer was developed for in-magnet whole-body human exercise testing. Designed on the basis of conventional mechanically braked bicycle ergometers and constructed from nonferrous materials, the ergometer was implemented on a 1.5-T whole-body MR scanner. A spectrometer interface was constructed using standard scanner hardware, complemented with custom-built parts and software to enable gated data acquisition during exercise. High-quality 31P NMR spectra were reproducibly obtained from the medial head of the quadriceps muscle of the right leg of eight healthy subjects during two-legged high-frequency pedaling (80 revolutions per minute) at three incremental workloads, including maximal. Muscle phosphocreatine content dropped 82%, from 32.2+/-1.0 mM at rest to 5.7+/-1.1 mM at maximal workload (mean+/-standard error; n=8), indicating that the majority of quadriceps motor units were recruited. The cardiovascular load of the exercise was likewise significant, as evidenced by heart rates of 150 (+/-10%) beats per minute, measured immediately afterward. As such, the newly developed MR bicycling exercise equipment offers a powerful new tool for clinical musculoskeletal and cardiovascular MR investigation. The basic design of the ergometer is highly generic and adaptable for application on a wide selection of whole-body MR scanners. |
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Authors:
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Jeroen A L Jeneson; Joep P J Schmitz; Peter A J Hilbers; Klaas Nicolay |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine Volume: 63 ISSN: 1522-2594 ISO Abbreviation: Magn Reson Med Publication Date: 2010 Jan |
Date Detail:
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Created Date: 2009-12-28 Completed Date: 2010-03-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8505245 Medline TA: Magn Reson Med Country: United States |
Other Details:
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Languages: eng Pagination: 257-61 Citation Subset: IM |
Copyright Information:
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Copyright (c) 2009 Wiley-Liss, Inc. |
Affiliation:
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Biomedical NMR, Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, the Netherlands. j.a.l.jeneson@tue.nl |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Artifacts* Equipment Design Equipment Failure Analysis Exercise Test / instrumentation* Humans Image Enhancement / instrumentation* Magnetic Resonance Imaging / instrumentation* Magnetics / instrumentation* Reproducibility of Results Sensitivity and Specificity Whole Body Imaging / instrumentation* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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