Document Detail

MR colonography with barium-based fecal tagging: initial clinical experience.
MedLine Citation:
PMID:  11930074     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To assess a strategy for fecal tagging with barium sulfate as an inexpensive tagging agent in conjunction with magnetic resonance (MR) colonography in patients suspected of having colorectal lesions. MATERIALS AND METHODS: Twenty-four patients suspected of having colonic lesions because of rectal bleeding, positive fecal occult blood test results, or altered bowel habits underwent MR colonography and subsequent conventional colonoscopy. A 200-mL dose of a barium sulfate-containing contrast agent was ingested with each of four low-fiber meals, beginning 36 hours before the examination. For MR colonography, the colon was filled with tap water. Gadobenate dimeglumine was injected intravenously. Images were acquired 75 seconds after gadobenate dimeglumine administration by using only a T1-weighted three-dimensional gradient-echo sequence. Images were reviewed by two radiologists blinded to conventional colonoscopic data. By using colonoscopy as the reference standard, sensitivity and specificity of MR colonography were determined for detecting colorectal masses. RESULTS: On the basis of MR colonography, 15 polyps of 5-20 mm and 10 carcinomas were detected and later confirmed with conventional colonoscopy. Conventional colonoscopy depicted three additional lesions less than 8 mm in diameter. Thus, sensitivity of MR colonography was 89.3% (25 of 28) for lesions and 91.7% (22 of 24) for patients. CONCLUSION: Barium-tagged MR colonography obviates bowel cleansing and depicts all lesions exceeding 8 mm in diameter.
Thomas C Lauenstein; Susanne C Goehde; Stefan G Ruehm; Gerald Holtmann; Jörg F Debatin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Radiology     Volume:  223     ISSN:  0033-8419     ISO Abbreviation:  Radiology     Publication Date:  2002 Apr 
Date Detail:
Created Date:  2002-04-03     Completed Date:  2002-06-04     Revised Date:  2006-01-16    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  248-54     Citation Subset:  AIM; IM    
Department of Diagnostic Radiology, University Hospital Essen, Hufelandstrasse 55, D-45122 Essen, Germany.
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MeSH Terms
Barium Sulfate / diagnostic use*
Colorectal Neoplasms / pathology*,  radiography*
Contrast Media*
Magnetic Resonance Imaging*
Middle Aged
Reg. No./Substance:
0/Contrast Media; 7727-43-7/Barium Sulfate
Comment In:
Z Gastroenterol. 2003 Jun;41(6):625-6   [PMID:  16279015 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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