Document Detail


MR and clinical follow-up of diffusion-weighted cerebral lesions after carotid artery stenting.
MedLine Citation:
PMID:  16219842     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: The purpose of this prospective study was to determine the outcome of postprocedural cerebral diffusion-weighted (DW) MR lesions after carotid artery stent placement (CAS) and the incidence of new cerebral MR lesions 6 months after the procedure. MATERIALS AND METHODS: DW and T2-weighted MR imaging of the brain and neurologic examinations were performed in 105 patients before and 24 hours and 6 months after CAS. In addition, a selective control angiography of the treated artery was performed after 6 months. RESULTS: In 22 (21%) of 105 patients, DW MR images 24 hours after CAS showed 64 new neurologically silent lesions; 2 (3.1%) of these 64 lesions were also visible in T2-weighted MR images. The latter ones were still visible after 6 months. In the remaining 62 lesions, there were no abnormalities visible in DW and T2-weighted imaging at follow-up. In 2 (1.9%) of the 105 patients, new cerebral lesions were seen in T2-weighted images after 6 months; one patient was neurologically symptomatic. All others patients were neurologically unremarkable at 6-month follow-up. CONCLUSIONS: Most postprocedural DW lesions showed no manifestations at 6-month MR follow-up and were clinically silent. This indicates that these lesions are potentially reversible and of no major neurologic sequelae. In addition, follow-up 6 months after CAS showed a very low incidence of new cerebral lesions and neurologic events.
Authors:
Elke A M Hauth; Christian Jansen; Robert Drescher; Michael Schwartz; Michael Forsting; Horst J Jaeger; Klaus D Mathias
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  AJNR. American journal of neuroradiology     Volume:  26     ISSN:  0195-6108     ISO Abbreviation:  AJNR Am J Neuroradiol     Publication Date:  2005 Oct 
Date Detail:
Created Date:  2005-10-12     Completed Date:  2005-11-21     Revised Date:  2008-02-14    
Medline Journal Info:
Nlm Unique ID:  8003708     Medline TA:  AJNR Am J Neuroradiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2336-41     Citation Subset:  IM    
Affiliation:
Department of Radiology, Klinikum Dormund, Dormund, Federal Republic of Germany.
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Angioplasty, Balloon / adverse effects
Brain / pathology*
Carotid Artery Diseases / pathology,  therapy*
Carotid Stenosis / diagnosis,  therapy
Diffusion Magnetic Resonance Imaging
Female
Humans
Magnetic Resonance Imaging*
Male
Middle Aged
Stents* / adverse effects

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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