Document Detail


MR characterization of blood flow in native and grafted internal mammary arteries.
MedLine Citation:
PMID:  8324302     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In the postoperative patient with anginal symptoms, differentiation between bypass graft compromise and nonischemic causes has until now been accomplished only by means of x-ray angiography. A non-invasive test is clearly desirable. The authors used a cine phase-contrast (PC) magnetic resonance (MR) imaging technique to characterize blood flow in native and grafted internal mammary arteries (IMAs). Ten volunteers and 15 patients who had recently undergone IMA coronary artery bypass grafting were imaged. Cine PC MR imaging was performed in the transaxial plane at the level of the pulmonary artery bifurcation. Flow in both IMAs was quantified and expressed as a percentage of cardiac output measured in the ascending aorta. In the 15 patients, flow analysis was performed in both the native and grafted IMAs. In the volunteers, IMA blood flow ranged from 2.1% to 4.3% of cardiac output on the left (mean, 3.5%) and 2.1% to 5.1% (mean, 3.5%) on the right. There was considerable intersubject variability, with coefficients of variation of 10.7% for the left and 12.3% for the right IMA. Intrasubject variability was limited, with estimated common standard deviations of 0.45% of cardiac output (range, 0.2%-1.1%) for the left and 0.39% (range, 0.1%-0.6%) for the right IMA. Flow in grafted IMAs was identified in 13 of 15 patients. In one of two patients without demonstrable IMA graft flow, cardiac catheterization confirmed lack of flow. IMA graft flow varied from 28 to 164 mL/min (mean, 80.3 mL/min). This study shows the feasibility of using cine PC MR imaging as a quantitative method of evaluating blood flow in IMA coronary artery bypass grafts.
Authors:
J F Debatin; J A Strong; H D Sostman; R Negro-Vilar; S S Paine; J M Douglas; N J Pelc
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of magnetic resonance imaging : JMRI     Volume:  3     ISSN:  1053-1807     ISO Abbreviation:  J Magn Reson Imaging     Publication Date:    1993 May-Jun
Date Detail:
Created Date:  1993-08-12     Completed Date:  1993-08-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9105850     Medline TA:  J Magn Reson Imaging     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  443-50     Citation Subset:  IM    
Affiliation:
Department of Radiology, Stanford University Medical Center, CA 94305.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Blood Flow Velocity*
Coronary Artery Bypass*
Female
Humans
Magnetic Resonance Imaging*
Male
Mammary Arteries / physiopathology*,  transplantation
Middle Aged

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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