Document Detail

An MR-based technique for quantifying the deformation of articular cartilage during mechanical loading in an intact cadaver joint.
MedLine Citation:
PMID:  9581616     Owner:  NLM     Status:  MEDLINE    
The objective of this study was to develop an MR-based technique for quantifying the deformation of articular cartilage during mechanical loading in an intact cadaver joint at high spatial and temporal resolution. A nonmetallic pressure device was constructed for applying loads of >1000 N to a femoro-patellar articulation within an extremity coil of a clinical 1.5 T MRI scanner. Digital image processing methods were used to determine the location- and time-dependent cartilage deformation in consecutive 2D fat-suppressed FLASH images. Additionally, three-dimensional reconstruction of the cartilage was performed from 3D fat-suppressed FLASH image data. During the first 10 min of static compression, thickness changes between 10 and 30% were observed. Thickness changes greater than 50% and volume changes of 20% were recorded after 3 h. The technique permits analysis of the load and time-dependent mechanical behavior of articular cartilage in its natural environment.
C Herberhold; T Stammberger; S Faber; R Putz; K H Englmeier; M Reiser; F Eckstein
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine     Volume:  39     ISSN:  0740-3194     ISO Abbreviation:  Magn Reson Med     Publication Date:  1998 May 
Date Detail:
Created Date:  1998-06-24     Completed Date:  1998-06-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8505245     Medline TA:  Magn Reson Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  843-50     Citation Subset:  IM; S    
Anatomische Anstalt, Ludwig Maximilians Universität München, Germany.
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MeSH Terms
Cartilage, Articular / anatomy & histology*,  physiology
Image Processing, Computer-Assisted / methods
Knee Joint / anatomy & histology*,  physiology
Magnetic Resonance Imaging / methods*
Weight-Bearing / physiology

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