| MR-arterioportography: a new technical approach for detection of liver lesions. | |
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MedLine Citation:
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PMID: 21483635 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIM: To evaluate the benefit and effectiveness of MR-arterioportography (MR-AP) to achieve the highest sensitivity for detection and evaluation of hepatocellular carcinoma (HCC). METHODS: Twenty liver cirrhosis patients with suspected HCC were included before transarterial chemoembolization. In all patients double-enhanced Magnetic resonance imaging (MRI) was performed. A bolus of 10 mL Magnevist® was injected through a selectively placed catheter in the superior mesenteric artery and MRI of the liver was performed in arterioportographic phase. Two independent readers evaluated number, size and localization of detected lesions. Diagnostic quality was determined using a 4-point scale. Differences were analyzed for significance using a t-test. Interobserver variability was calculated. RESULTS: In all 20 patients (100%), MR-AP was feasible. Diagnostic quality was, in all cases, between 1 and 2 for both modalities and readers. MR-AP detected significantly more lesions than double-enhanced MRI (102.5 vs. 61, respectively, P < 0.0024). The inter-observer variability was 0.881 for MRI and 0.903 for MR-AP. CONCLUSION: Our study confirmed that the MR-AP as an additional modality for detection of HCC is beneficial, as significantly more lesions were detected compared to MRI with liver-specific contrast. |
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Authors:
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Janine Rennert; Ernst-Michael Jung; Andreas G Schreyer; Patrick Hoffstetter; Peter Heiss; Stefan Feuerbach; Niels Zorger |
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Publication Detail:
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Type: Evaluation Studies; Journal Article |
Journal Detail:
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Title: World journal of gastroenterology : WJG Volume: 17 ISSN: 1007-9327 ISO Abbreviation: World J. Gastroenterol. Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-04-12 Completed Date: 2011-07-20 Revised Date: 2011-07-28 |
Medline Journal Info:
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Nlm Unique ID: 100883448 Medline TA: World J Gastroenterol Country: China |
Other Details:
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Languages: eng Pagination: 1739-45 Citation Subset: IM |
Affiliation:
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Department of Radiology, Regensburg University School of Medicine, D-93053 Regensburg, Germany. jarennert@yahoo.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Carcinoma, Hepatocellular / diagnosis*, pathology* Female Humans Liver Diseases / diagnosis, pathology Liver Neoplasms / diagnosis*, pathology*, virology Magnetic Resonance Imaging / methods* Male Middle Aged Portography / methods* Sensitivity and Specificity |
| Comments/Corrections | |
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