Document Detail

M13 phage DNA as a universal marker for DNA fingerprinting of animals, plants and microorganisms.
MedLine Citation:
PMID:  2838336     Owner:  NLM     Status:  MEDLINE    
Hypervariable polymorphic patterns were detected with M13 phage DNA as a probe in genomic DNA of organisms belonging to different taxonomic groups including animals (vertebrates and invertebrates), plants and microorganisms. Individual-specific restriction pattern analysis (DNA fingerprinting) with this probe proved to be useful for individual identification, analysis of somatic stability and paternity testing in man. The nuclear type of inheritance indicates that the hypervariable DNA regions in question are located in the chromosomes, not in the mitochondrial DNA. The data obtained also demonstrate a potential range of M13 DNA applications as a probe for DNA fingerprinting of animals, plants and microorganisms, particularly for the determination of inbred lines, identification of bacterial strains and establishing stock, variety and strain distinctions.
A P Ryskov; A G Jincharadze; M I Prosnyak; P L Ivanov; S A Limborska
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  FEBS letters     Volume:  233     ISSN:  0014-5793     ISO Abbreviation:  FEBS Lett.     Publication Date:  1988 Jun 
Date Detail:
Created Date:  1988-08-08     Completed Date:  1988-08-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0155157     Medline TA:  FEBS Lett     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  388-92     Citation Subset:  IM    
Institute of Molecular Biology, USSR Academy of Sciences, Moscow.
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MeSH Terms
Coliphages / genetics
DNA / genetics*,  isolation & purification
DNA Restriction Enzymes
DNA, Viral / genetics*
Escherichia coli / genetics
Plants / genetics
Polymorphism, Genetic*
Species Specificity
Reg. No./Substance:
0/DNA, Viral; 9007-49-2/DNA; EC 3.1.21.-/DNA Restriction Enzymes

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