Document Detail

M-mode echocardiography overestimates left ventricular mass in patients with normal left ventricular shape: a comparative study using three-dimensional echocardiography.
MedLine Citation:
PMID:  14611828     Owner:  NLM     Status:  MEDLINE    
AIMS: We sought to evaluate whether left ventricular (LV) mass (M) determined by M-mode echocardiography is overestimated compared with LVM calculated by three-dimensional (3D) echocardiography (E) in patients with normal LV shape. METHODS AND RESULTS: A total of 112 studies in 56 patients (60+/-13 years) with hypertension (n=25) or aortic stenosis (n=31) and 30 control subjects (57+/-14 years) evaluated for cardiac sources of embolism were analyzed. LVM by M-mode and 3DE was highly correlated (r=0.85; p<0.001). However, there were broad limits of agreement (-58 to 110 g) demonstrating large variability between the methods. M-mode overestimated 3DE LVM by a mean of 15+/-24% (p<0.001) with overestimation in controls and the different patient groups. Variability was unrelated to increasing quartiles of LVM values. Using technique-specific partition values for normal LVM, the agreement between M-mode and 3DE for the detection of LV hypertrophy was 83% (Kappa=0.59; p<0.001). CONCLUSION: Although M-mode and 3DE correlate well for the calculation of LVM, there is a systematic difference between the two techniques leading to overestimation of LVM by the 1D technique. Thus, previously published cutoff values for normal LVM derived from M-mode may not apply for 3DE. However, the use of technique-specific partition values allows stratification of patients for the presence of LV hypertrophy with reasonable agreement.
H P Kühl; P Hanrath; A Franke
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology     Volume:  4     ISSN:  1525-2167     ISO Abbreviation:  Eur J Echocardiogr     Publication Date:  2003 Dec 
Date Detail:
Created Date:  2003-11-12     Completed Date:  2004-03-31     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  100890618     Medline TA:  Eur J Echocardiogr     Country:  England    
Other Details:
Languages:  eng     Pagination:  312-9     Citation Subset:  IM    
Medizinische Klinik I, Universitätsklinikum Aachen, Aachen, Germany.
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MeSH Terms
Diagnostic Errors
Echocardiography, Three-Dimensional*
Heart Ventricles / ultrasonography*
Hypertrophy, Left Ventricular / ultrasonography*
Middle Aged
Comment In:
Eur J Echocardiogr. 2004 Aug;5(4):243; author reply 244   [PMID:  15219537 ]

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