Document Detail


M-mode echocardiographic findings in a contemporary Afro-Caribbean population referred for evaluation of congestive cardiac failure.
MedLine Citation:
PMID:  12232949     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Congestive cardiac failure is emerging as a significant public health problem around the world, including the Caribbean. Recent reports from developed countries suggest that 30 to 40% of patients with congestive cardiac failure have normal systolic function. This percentage may be even higher in non-Caucasian, non-male populations. This study was undertaken to determine the M-mode echocardiographic findings in a current, consecutive series of Afro-Caribbean patients referred for congestive cardiac failure. There were 165 patients, 51% male, mean and standard deviation (SD) age of 63 +/- 15 years, referred between May 1998 and June 2000. Echocardiographic findings included left atrial size (LA), left ventricular (LV) end systolic (ESD) and end diastolic dimension (EDD), LV posterior wall thickness (PWT) and ventricular septal thickness (VST). LV ejection fraction (EF) was derived. LA > 4 cm, PWT or VST > 13 mm and LVEF < 50% were considered abnormal. Increased LV wall thickness (LV hypertrophy) only was the most frequent finding, 68/165 (41%), consistent with possible diastolic dysfunction. If a less restrictive definition for abnormal LV wall thickness, 12 mm, is used, this finding increases to 79/165 (48%). Decreased LVEF (LV systolic dysfunction) was seen in 57/165, (35%) and was seen in significantly more men (42% versus 29%, p < 0.01). Valvular disease was seen in 13/165, 8%. Normal findings on echocardiography were found in 27/165 (16%), more commonly in women (19 versus 8, p < 0.05) and younger patients (54 years versus 65 years, p < 0.05) and in only 10% if 12 mm is used for LV wall limit. LV hypertrophy was seen in 42% of patients (61% if 12 mm is used for LV wall limit) with systolic dysfunction. Thus, congestive cardiac failure with LV hypertrophy is the most frequent finding in this Afro-Caribbean population, with LV systolic dysfunction in only 35% of patients. These findings are consistent with possible diastolic LV dysfunction due to hypertension as the primary cause of cardiac failure in the population.
Authors:
T C Martin
Related Documents :
21052009 - Myocardial fibrosis attenuates the effect of cibenzoline on left ventricular diastolic ...
19502969 - Cardiac dysfunction after renal transplantation; incomplete resolution in pediatric pop...
10492839 - Different prognostic significance of right and left ventricular diastolic dysfunction i...
11842039 - Wall stress misrepresents afterload in children and young adults with abnormal left ven...
20384649 - Left ventricular extracellular matrix remodeling in dogs with right ventricular apical ...
6210459 - Regression of myocardial hypertrophy: electrocardiographic-echocardiographic correlatio...
23706109 - Is early ventricular dysfunction or dilatation associated with lower mortality rate in ...
22948409 - Hydrogen sulfide postconditioning protects isolated rat hearts against ischemia and rep...
2146309 - Coronary hemodynamic effects of atrial natriuretic peptide in humans.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The West Indian medical journal     Volume:  51     ISSN:  0043-3144     ISO Abbreviation:  West Indian Med J     Publication Date:  2002 Jun 
Date Detail:
Created Date:  2002-09-17     Completed Date:  2002-10-02     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  0417410     Medline TA:  West Indian Med J     Country:  Jamaica    
Other Details:
Languages:  eng     Pagination:  93-6     Citation Subset:  IM    
Affiliation:
Cardiology Service, Holberton Hospital, St John's, Antigua, WI. martint@candw.ag
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
African Continental Ancestry Group
Aged
Aged, 80 and over
Antigua and Barbuda
Echocardiography*
Female
Heart Failure / ultrasonography*
Humans
Male
Middle Aged

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Socio-demographic and health system factors in relation to exclusive breast-feeding in Tobago.
Next Document:  A survey of essential national health research in nine developing countries.