| Lysine vasopressin fails to alter (3H)-noradrenaline uptake or release from hippocampal tissue in vitro. | |
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MedLine Citation:
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PMID: 6855454 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Lysine vasopressin (5.2 and 10.4 microM) failed to significantly alter the spontaneous release of (3H)-noradrenaline from hippocampal slices in vitro or the release observed after stimulation with potassium chloride (15 and 25 mM). Uptake of (3H)-noradrenaline by synaptosomes prepared from hippocampal tissue was not significantly changed by incubation with vasopressin (5.2 and 10.4 mu M). Our results fail to support the hypothesis, derived from behavioural and in vivo biochemical studies, that vasopressin modulates the activity of noradrenergic nerve terminals in this part of the limbic system. |
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Authors:
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J J Hagan; D J Balfour |
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Publication Detail:
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Type: In Vitro; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Life sciences Volume: 32 ISSN: 0024-3205 ISO Abbreviation: Life Sci. Publication Date: 1983 May |
Date Detail:
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Created Date: 1983-07-15 Completed Date: 1983-07-15 Revised Date: 2009-11-19 |
Medline Journal Info:
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Nlm Unique ID: 0375521 Medline TA: Life Sci Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 2517-22 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Hippocampus / drug effects, metabolism* Lypressin / pharmacology* Male Norepinephrine / metabolism* Potassium Chloride / pharmacology Rats |
| Chemical | |
Reg. No./Substance:
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50-57-7/Lypressin; 51-41-2/Norepinephrine; 7447-40-7/Potassium Chloride |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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