Document Detail

Lymphscintigraphy predicts response to complex physical therapy in patients with early stage extremity lymphedema.
MedLine Citation:
PMID:  18365531     Owner:  NLM     Status:  MEDLINE    
We investigated whether baseline lymphscintigraphic findings can predict long-term response to complex physical therapy (CPT) in patients with early stage extremity lymphedema. Twenty patients with unilateral extremity lymphedema of clinical stage I or II underwent CPT after baseline lymphscintigraphy. Therapeutic responses (good vs. poor) were evaluated at 1 year post-CPT based on changes in skin status and subjective symptoms, and percent volume reductions and compared with clinical factors and lymphscintigraphic findings. Eleven patients showed good response to CPT with significant volume reduction of edematous extremities, and no significant volume reduction was observed in the remaining 9. Patients with good or poor responses to CPT showed no significant differences in terms of clinical variables. However, significant differences were observed between the lymphscintigraphic findings of these patients. More specifically, a lymphscintigraphic finding of main lymphatic vessels without collateral lymphatic vessels was the best predictor for a good response to CPT; the sensitivity, specificity and accuracy of this lymphscintigraphic finding is 91% (10/11), 100% (9/9) and 95% (19/20), respectively. In patients with unilateral extremity lymphedema of early stage, baseline lymphscintigraphy may usefully predict long-term response to CPT.
J H Hwang; J Y Choi; J Y Lee; S H Hyun; Y Choi; Y S Choe; K H Lee; B T Kim
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Lymphology     Volume:  40     ISSN:  0024-7766     ISO Abbreviation:  Lymphology     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2008-03-27     Completed Date:  2008-06-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0155112     Medline TA:  Lymphology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  172-6     Citation Subset:  IM    
Department of Physical Medicine and Rehabilitation, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
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MeSH Terms
Antimony / diagnostic use
Lymphatic System / radionuclide imaging*
Lymphedema / radionuclide imaging,  therapy*
Middle Aged
Physical Therapy Modalities*
Sensitivity and Specificity
Technetium Compounds / diagnostic use
Reg. No./Substance:
0/Technetium Compounds; 0/technetium Tc 99m antimony sulfide; 7440-36-0/Antimony

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