Document Detail

Lymphoma-like lesions of the endometrium
MedLine Citation:
PMID:  19084721     Owner:  NLM     Status:  MEDLINE    
Chronic endometritis is a rare entity characterized by an endometrial plasmocytic infiltrate. The lymphoid infiltrate may be abundant and simulate a lymphoma of the uterus. We report two cases of lymphoma-like lesions of the endometrium in two postmenopausal women of 79 and 89 year-old, who presented with abundant vaginal discharge. Ultrasound examination revealed in both cases an intrauterin polypoid lesion. Histologically, a predominantly plasmocytic infiltrate was seen in the endometrium destroying endometrial glandes and extending into the superficial myometrium, in the first case. Immunohistochemical study showed a polymorphic lymphoid infiltrate with a predominance of Tcells. Molecular study revealed a polyclonalB cell population, distinguishing the lesion from a marginal zone lymphoma. Lymphoma-like lesions of female genital tract must be distinguished from malignant lymphoma that rarely occurs in this site.
Lucie Gaillot; Fabienne Allias; Gil Dubernard; Françoise Berger; Mojgan Devouassoux-Shisheboran
Publication Detail:
Type:  Case Reports; English Abstract; Journal Article     Date:  2008-11-17
Journal Detail:
Title:  Annales de pathologie     Volume:  28     ISSN:  0242-6498     ISO Abbreviation:  Ann Pathol     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2008-12-16     Completed Date:  2009-02-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8106337     Medline TA:  Ann Pathol     Country:  France    
Other Details:
Languages:  fre     Pagination:  504-7     Citation Subset:  IM    
Service d'anatomie et cytologie pathologiques des hôpitaux Nord, centre de biologie et pathologie Nord, hôpital de la Croix-Rousse, 103 Grande-Rue de la Croix-Rousse, 69317 Lyon cedex 04, France.
Vernacular Title:
Endométrite chronique pseudolymphomateuse.
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MeSH Terms
Aged, 80 and over
B-Lymphocytes / pathology
Diagnosis, Differential
Endometrium / pathology*
Lymphoma / pathology*
T-Lymphocytes / pathology
Uterine Neoplasms / pathology

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