Document Detail


Lymphoma in Sjogren's syndrome.
MedLine Citation:
PMID:  1608349     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Sjogren's syndrome is an autoimmune disease with a known predisposition for lymphoma development. Eight of 120 patients with primary Sjogren's syndrome followed at the University of Ioannina over the past 7 years developed non-Hodgkin's lymphoma diagnosed according to the Kiel classification. The lymphomas differed by location and grading. Six were called low grade (immunocytoma) and two intermediate grade non-Hodgkin's lymphomas. Five of the immunocytomas involved the minor salivary or lacrimal glands. Immunoperoxidase staining for light chains revealed monoclonal populations. Two patients showed spontaneous regression not previously reported in Sjogren's syndrome. Thus, in Sjogren's syndrome, low grade non-Hodgkin's lymphomas and especially immunocytomas are the most common lymphomas. These lymphomas tend to evolve very slowly and may regress spontaneously. Given these facts, a conservative approach to treatment is indicated in those patients with only localized disease.
Authors:
N A Pavlidis; A A Drosos; C Papadimitriou; N Talal; H M Moutsopoulos
Related Documents :
18193229 - Correspondence between clinical improvement and proteomic changes of the salivary pepti...
8884139 - Update on sjögren-larsson syndrome.
8646439 - 'seronegative' sjögren's syndrome manifested as a subset of chronic fatigue syndrome.
7849389 - T cell abnormalities in mixed connective tissue disease complicated with klinefelter's ...
1419499 - New developments in sjögren's syndrome.
111679 - Immunoblastic sarcoma with features of sjögren's syndrome and systemic lupus erythemat...
7648039 - Richner-hanhart syndrome (tyrosinemia type ii). case report and literature review.
17256569 - Massive pulmonary embolism secondary to anticardiolipin antibody syndrome.
18162369 - Pathogenesis of pr3-anca associated vasculitis.
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Medical and pediatric oncology     Volume:  20     ISSN:  0098-1532     ISO Abbreviation:  Med. Pediatr. Oncol.     Publication Date:  1992  
Date Detail:
Created Date:  1992-07-23     Completed Date:  1992-07-23     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7506654     Medline TA:  Med Pediatr Oncol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  279-83     Citation Subset:  IM    
Affiliation:
Department of Medicine and Pathology, Medical School, University of Ioannina, Greece.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Autoimmune Diseases / complications*
Female
Humans
Immunoenzyme Techniques
Lymphoma, Non-Hodgkin / etiology*,  pathology
Middle Aged
Remission, Spontaneous
Sjogren's Syndrome / complications*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Cranial computed tomographic findings in children with newly diagnosed acute lymphoblastic leukemia:...
Next Document:  N-myc gene amplification in neuroblastoma: a clinical approach using ultrasound guided cutting needl...