Document Detail

Lymphoepithelial cyst of the pancreas with sebaceous differentiation.
MedLine Citation:
PMID:  10832677     Owner:  NLM     Status:  MEDLINE    
We recently encountered a patient with a lymphoepithelial cyst of the pancreas with sebaceous differentiation. We sought to compare the characteristics of this patient with those previously reported in order to foster a keener understanding of this rare clinical entity. After reviewing the present patient's case in detail, we conducted a comprehensive review of the English-language literature and analyzed the clinical characteristics of reported cases of lymphoepithelial cysts. Our patient was an asymptomatic 60-year-old man who presented with an incidental finding of a cystic lesion in the tail of the pancreas documented by computed tomography. The cyst was enucleated, and was found to contain keratinized material. It was lined by squamous epithelium with small sebaceous glands, and surrounded by lymphoid tissue with germinal centers. Of 33 reported cases, only 6 (18%) contained sebaceous glands. In all patients who underwent operation, the cysts were easily resected, and the outcome was favorable. Lymphoepithelial cyst of the pancreas is rare, and may be difficult to differentiate from cystic neoplasms preoperatively. Therefore resection is indicated. The diagnosis, however, can be confirmed by careful histologic review, and the prognosis is excellent.
H Fujiwara; N Kohno; S Nakaya; Y Ishikawa
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Journal of gastroenterology     Volume:  35     ISSN:  0944-1174     ISO Abbreviation:  J. Gastroenterol.     Publication Date:  2000  
Date Detail:
Created Date:  2000-09-14     Completed Date:  2000-09-14     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9430794     Medline TA:  J Gastroenterol     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  396-401     Citation Subset:  IM    
Department of Surgery, Hyogo Medical Center for Adults, Akashi, Japan.
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MeSH Terms
Diagnosis, Differential
Epithelial Cells / pathology*
Lymphocele / pathology*,  radiography,  surgery
Magnetic Resonance Imaging
Middle Aged
Pancreatic Cyst / pathology*,  radiography,  surgery
Tomography, X-Ray Computed

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