Document Detail

Lymphocytic leukemia and exposures to benzene and other solvents in the rubber industry.
MedLine Citation:
PMID:  6886869     Owner:  NLM     Status:  MEDLINE    
Previous epidemiological studies on one cohort of rubber industry workers indicated that observed mortality excesses from lymphocytic leukemia were related to solvent exposures. The results of a detailed examination of the solvent exposure histories of 15 cases of lymphocytic leukemia from this cohort and 30 matched industry controls are presented. Extensive review of historical solvent use, raw materials specifications and job description records were used to reconstruct exposures to specific agents. Cases were 4.5 times as likely as controls to have had direct exposures to both benzene and other solvents. Analysis by manufacturing production source of solvent revealed that cases spent greater proportions of their work experience in jobs with potential exposures to coal tar-based benzene and xylene. No differences were seen for petroleum-derived solvents.
E W Arp; P H Wolf; H Checkoway
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of occupational medicine. : official publication of the Industrial Medical Association     Volume:  25     ISSN:  0096-1736     ISO Abbreviation:  J Occup Med     Publication Date:  1983 Aug 
Date Detail:
Created Date:  1983-10-28     Completed Date:  1983-10-28     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7502807     Medline TA:  J Occup Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  598-602     Citation Subset:  IM    
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MeSH Terms
Benzene / adverse effects*
Leukemia, Lymphoid / chemically induced*,  epidemiology
Middle Aged
Occupational Diseases / chemically induced*,  epidemiology
Solvents / adverse effects*
Xylenes / adverse effects
Reg. No./Substance:
0/Solvents; 0/Xylenes; 71-43-2/Benzene; 9006-04-6/Rubber

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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