Document Detail

Lymphocytic hypophysitis with normal pituitary function mimicking a pituitary adenoma: a case report and review of literature.
MedLine Citation:
PMID:  20040330     Owner:  NLM     Status:  MEDLINE    
Lymphocytic hypophysitis (LYH) is a rare autoimmune inflammatory disorder of the pituitary gland usually affecting young women, often in pregnancy or post partum period. It is rare in non-pregnant females and in men. Patients present with symptoms of an expanding pituitary mass and/or varying degrees of pituitary dysfunction. We, hereby report a case of lymphocytic hypophysitis in a 28-year-old non-pregnant female who presented with clinical and radiological features of a pituitary tumor with normal pituitary hormones which on histopathological examination revealed features of lymphocytic hypophysitis. The case is presented here for its rarity and its unique presentation as an expanding pituitary mass with normal pituitary function. Peculiar clinical, radiological and histopathological features of this uncommon entity are discussed.
M Rumana; A Kirmani; N Khursheed; S Besina; M Khalil
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Clinical neuropathology     Volume:  29     ISSN:  0722-5091     ISO Abbreviation:  Clin. Neuropathol.     Publication Date:    2010 Jan-Feb
Date Detail:
Created Date:  2009-12-30     Completed Date:  2010-03-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8214420     Medline TA:  Clin Neuropathol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  26-31     Citation Subset:  IM    
Departments of Pathology, SKIMS, Kashmir, India.
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MeSH Terms
Autoimmune Diseases of the Nervous System / diagnosis*,  pathology*
Brain / pathology
Diagnosis, Differential
Magnetic Resonance Imaging
Pituitary Diseases / diagnosis*,  pathology*
Pituitary Neoplasms / diagnosis*,  pathology*

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